Protein Alignment Cyp313a5 and Cyp3a16

DIOPT Version :10

• Sequence 1: NP_650168.1
• Gene: Cyp313a5 / 41486
• FlyBaseID: FBgn0038005
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_031846.2
• Gene: Cyp3a16 / 13114
• MGIID: 106099
• Length: 504
• Species: Mus musculus
• Alignment Length: 487
• Identity: 121/487 - (24%)
• Similarity: 217/487 - (44%)
• Gaps: 63/487 - (12%)

  Fly     2 LTLQIFEAFAIIL--------CVYFLWSRRRFYIMMLKLPGPMGFPFIGLAFEYIRLKRKIRLRT 58
            |:|......||||        |.:.|:.::       .:|||...||:|....|.:...|..:.
Mouse     7 LSLDTLVLLAIILVLLYRYGTCTHGLFKKQ-------GIPGPKPLPFLGTVLNYYKGLWKFDME- 63

  Fly    59 ILFKIYGKTVLTWIGLTPVLVTCEPKILEDIFTSPNC----SNRS-----SVVDKAISSCLGLGL 114
             .::.||||...:.|..|:.|..:|:.::::... .|    :||.     .::.|:||
Mouse    64 -CYEKYGKTWGLFDGQIPLFVITDPETIKNVLVK-ECFSVFTNRQDFFPVGIMSKSIS------- 119

  Fly   115 LTLKNNHWNERRKLLLPSFKNNAVLSFVPVLNNEANFLVTLLAEFVD-GGDINLLPELNKWSFKI 178
             ..|:..|...|.||.|:|.:..:....||:....:.||..|.:..: |..:.:...|..:|..:
Mouse   120 -LAKDEEWKRYRALLSPTFTSGNLKEMFPVIEQYGDILVKYLRQEAEKGKPVAVKDVLGAYSMDV 183

  Fly   179 AAQITMGDEVRNQANYQNGNLLESYKAL--NNLIPIGV---VMPWLRNKY-LGKLFSYEKRRLEA 237
            ....|.|..:.:..|.::..:..:.|.|  :...|:.:   :.|:|...| :..:..:.|..:|
Mouse   184 IISTTFGVNIDSLNNPEDPFVENAKKVLRFDYFDPLSLSVALFPFLTPIYEMLNICMFPKDSIE- 247

  Fly   238 ATQSNAFIKDIIDKKLSSTDNSSEPALIDRILNLVRIGELSYD----------DVMGEFSNIIFA 292
                  |.|..:|:...:..:|.:...:|.|..::.....|.|          ::..:....|||
Mouse   248 ------FFKKFVDRMTENRLDSKQKHRVDFIYLMMEAYNKSKDKDSHKALSEIEITAQSIIFIFA 306

  Fly   293 ASDTLSITVNNVLILMAMFPKYQDNVFEELAEVFPSGGEFEASHADLEKLVKLDRVLHETMRLIP 357
            ..:|.|..::..:..:|..|..|..:.||:.|..|:  :...::..:..:..||.||:||:||.|
Mouse   307 GYETTSSILSFTVYSLATHPDIQKKLQEEIDEALPN--KAPPTYDTVMAMEYLDMVLNETLRLYP 369

  Fly   358 AVPLLIRQTSHSIQLSNGFYIPEGVTLMIDIFHTHRNKDIWGPQANAFNPDNFLPENKRARPPYS 422
            ....|.|.....::: ||.|||:|.|::|..:..|.:...| |:...|.|:.|..|||.:..||.
Mouse   370 ITNRLQRVCKKDVEI-NGIYIPKGSTVIIPSYVLHHDPQHW-PEPEEFQPERFSKENKGSIDPYV 432

  Fly   423 YLPFSKGKKTCLGWKLSLISAKLALAKILRNY 454
            ||||..|.:.|:|.:.:|::.||||.|:|:|:
Mouse   433 YLPFGNGPRNCIGMRFALMNMKLALIKVLQNF 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a5	NP_650168.1	CYP313-like	65..482	CDD:410680	104/416 (25%)
Cyp3a16	NP_031846.2	CYP3A	67..493	CDD:410743	105/418 (25%)