Protein Alignment Cyp313a5 and Cyp3a11

DIOPT Version :10

• Sequence 1: NP_650168.1
• Gene: Cyp313a5 / 41486
• FlyBaseID: FBgn0038005
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_031844.1
• Gene: Cyp3a11 / 13112
• MGIID: 88609
• Length: 504
• Species: Mus musculus
• Alignment Length: 512
• Identity: 132/512 - (25%)
• Similarity: 234/512 - (45%)
• Gaps: 54/512 - (10%)

  Fly     2 LTLQIFEAFAIILCVYFLWSRRRFYIMMLK-LPGPMGFPFIGLAFEYIRLKRKIRLRTILFKIYG 65
            |:|:.:...||.|.:.:.:..|:..:...: :|||...||:|....|.:...|..:.  .:|.||
Mouse     7 LSLETWVLLAISLVLLYRYGTRKHELFKKQGIPGPKPLPFLGTVLNYYKGLWKFDME--CYKKYG 69

  Fly    66 KTVLTWIGLTPVLVTCEPKILED--------IFTSPNCSNRSSVVDKAISSCLGLGLLTLKNNHW 122
            ||...:.|.||:|...:|:.:::        :||:........::.||||        ..|::.|
Mouse    70 KTWGLFDGQTPLLAVTDPETIKNVLVKECFSVFTNRRDFGPVGIMSKAIS--------ISKDDEW 126

  Fly   123 NERRKLLLPSFKNNAVLSFVPVLNNEANFLVTLLAEFV-DGGDINLLPELNKWSFKIAAQITMGD 186
            ...|.||.|:|.:..:....||:....:.||..|.:.. .|..:.:...|..:|..:....:.|.
Mouse   127 KRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLRQKAKKGKPVTMKDVLGAYSMDVITSTSFGV 191

  Fly   187 EVRNQANYQNGNLLESYKAL-----NNLIPIGVVMPWLRNKY-LGKLFSYEKRRLEAATQSNAFI 245
            .|.:..|.::..:.::.|.|     :.|:...|:.|:|...| :..:..:.|..:|       |.
Mouse   192 NVDSLNNPEDPFVEKAKKLLRFDFFDPLLFSVVLFPFLTPVYEMLNICMFPKDSIE-------FF 249

  Fly   246 KDIIDKKLSSTDNSSEPALIDRILNLVRIGELSYD----------DVMGEFSNIIFAASDTLSIT 300
            |..:|:...|..:|.:...:|.:..::.....|.|          ::..:....|||..:|.|.|
Mouse   250 KKFVDRMKESRLDSKQKHRVDFLQLMMNSHNNSKDKVSHKALSDMEITAQSIIFIFAGYETTSST 314

  Fly   301 VNNVLILMAMFPKYQDNVFEELAEVFPSGGEFEASHADLEKLVKLDRVLHETMRLIPAVPLLIRQ 365
            ::..|..:|..|..|..:.:|:.|..|:  :...::..:.::..||.||:||:||.|....|.|.
Mouse   315 LSFTLHSLATHPDIQKKLQDEIDEALPN--KAPPTYDTVMEMEYLDMVLNETLRLYPIANRLERV 377

  Fly   366 TSHSIQLSNGFYIPEGVTLMIDIFHTHRNKDIWGPQANAFNPDNFLPENKRARPPYSYLPFSKGK 430
            ....::| ||.|||:|.|:||..:..|.:...|. :...|.|:.|..|||.:..||.||||..|.
Mouse   378 CKKDVEL-NGVYIPKGSTVMIPSYALHHDPQHWS-EPEEFQPERFSKENKGSIDPYVYLPFGNGP 440

  Fly   431 KTCLGWKLSLISAKLALAKILRNYMLSTTFLYKDLRFIDNTTMKLAEQPLLAVKRRI 487
            :.|||.:.:|::.||||.||::|:.....   |:.:.    .:||:.|.||..::.|
Mouse   441 RNCLGMRFALMNMKLALTKIMQNFSFQPC---KETQI----PLKLSRQGLLQPEKPI 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a5	NP_650168.1	CYP313-like	65..482	CDD:410680	114/441 (26%)
Cyp3a11	NP_031844.1	CYP3A	67..493	CDD:410743	117/450 (26%)