Protein Alignment Cyp313a5 and CYP4F22

DIOPT Version :9

• Sequence 1: NP_650168.1
• Gene: Cyp313a5 / 41486
• FlyBaseID: FBgn0038005
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_775754.2
• Gene: CYP4F22 / 126410
• HGNCID: 26820
• Length: 531
• Species: Homo sapiens
• Alignment Length: 534
• Identity: 128/534 - (23%)
• Similarity: 221/534 - (41%)
• Gaps: 96/534 - (17%)

  Fly     3 TLQIFEAFAII-LCVYFLWSRRRFYIMMLKL---PGPMGFP----FIGLAFEYIRLKRKIRLRTI 59
            ||.:|..|.:. |.:.||...|.|||...:|   |.|   |    .:|....|:..:..::....
Human    26 TLLLFLLFFLFRLLLRFLRLCRSFYITCRRLRCFPQP---PRRNWLLGHLGMYLPNEAGLQDEKK 87

  Fly    60 LFKIYGKTVLTWIG-LTPVLVTCEPKILEDIF-TSPNCSNRSSVVDKAISSCLGLGLLTLKNNHW 122
            :.......:|.|:| :.|:||...|..::.:. .|...:.:..:....:...||.|||..|.:.|
Human    88 VLDNMHHVLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGLLLSKGDKW 152

  Fly   123 NERRKLLLPSFKNNAVLSFVPVLNNEANFLVTLLAEFVDGGDINL----------LPELNK--WS 175
            :..|:||.|:|..:.:..::.:.|..|:.:........:|..::|          |..|.|  :|
Human   153 SRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHISLMTLDSLQKCVFS 217

  Fly   176 FKIAAQITMGDEVRNQANYQNGNLLESYKALNNLIPIGVVMPWLRNKYL---------GKLFS-- 229
            :....|..|.|.:               .|:..|..:.|...:..:.||         |:.|.
Human   218 YNSNCQEKMSDYI---------------SAIIELSALSVRRQYRLHHYLDFIYYRSADGRRFRQA 267

  Fly   230 ------------YEKRRLEAATQSNAFIK-------DIIDKKLSSTDNSSEPALIDRILNLVRIG 275
                        .|:||......:.|::|       |.||..|.:.|...:
Human   268 CDMVHHFTTEVIQERRRALRQQGAEAWLKAKQGKTLDFIDVLLLARDEDGK-------------- 318

  Fly   276 ELSYDDVMGEFSNIIFAASDTLSITVNNVLILMAMFPKYQDNVFEELAEVFPSGGEFEASHADLE 340
            |||.:|:..|....:|...||.|..::.:|..:|.:|:||:...||:.||.......|....||.
Human   319 ELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELEWDDLT 383

  Fly   341 KLVKLDRVLHETMRLIPAVPLLIRQTSHSIQLSNGFYIPEGVTLMIDIFHTHRNKDIWGPQANAF 405
            :|......:.|::|..|.|.|:.||.:..|:|.:|..||:|:..::.|:.||.|..:| |.:..:
Human   384 QLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLVSIYGTHHNPTVW-PDSKVY 447

  Fly   406 NPDNFLPENKRARPPYSYLPFSKGKKTCLGWKLSLISAKLALAKILRNYMLSTTFLYKDLRFIDN 470
            ||..|.|:|.:.|.|.:|:|||.|.:.|:|...::...::.:|..|..:.||.           :
Human   448 NPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSV-----------D 501

  Fly   471 TTMKLAEQPLLAVK 484
            .|.|:..:|.|.::
Human   502 RTRKVRRKPELILR 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a5	NP_650168.1	p450	33..458	CDD:299894	111/472 (24%)
CYP4F22	NP_775754.2	p450	60..524	CDD:278495	116/500 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810