Protein Alignment Cyp313a5 and CYP4F8

DIOPT Version :10

• Sequence 1: NP_650168.1
• Gene: Cyp313a5 / 41486
• FlyBaseID: FBgn0038005
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_009184.1
• Gene: CYP4F8 / 11283
• HGNCID: 2648
• Length: 520
• Species: Homo sapiens
• Alignment Length: 437
• Identity: 116/437 - (26%)
• Similarity: 184/437 - (42%)
• Gaps: 53/437 - (12%)

  Fly    54 IRLRTILFKIYGKTVLTWIG-LTPVLVTCEPKILEDIF-TSPNCSNRSSVVDKAISSCLGLGLLT 116
            :|:.|.|...|.:..:.|:| :||::..|.|.|:..:. ||...:::..|..|.:...||.|||.
Human    74 LRVLTQLVATYPQGFVRWLGPITPIINLCHPDIVRSVINTSDAITDKDIVFYKTLKPWLGDGLLL 138

  Fly   117 LKNNHWNERRKLLLPSFKNNAVLSFVPVLNNEANFLVTLLAEFVDGGDINL----------LPEL 171
            ...:.|...|:||.|:|..|.:..::.:.:..||.:..........|...|          |..|
Human   139 SVGDKWRHHRRLLTPAFHFNILKPYIKIFSKSANIMHAKWQRLAMEGSTCLDVFEHISLMTLDSL 203

  Fly   172 NKWSF--------KIAAQITMGDEVRNQANYQNGNLLESYKALNNLIPIGVVMPWLRNKYLGKLF 228
            .|..|        |.:..||...|:......:|.........|..|.|.|  ..:.|...|...|
Human   204 QKCIFSFDSNCQEKPSEYITAIMELSALVVKRNNQFFRYKDFLYFLTPCG--RRFHRACRLVHDF 266

  Fly   229 S----YEKRR----------LEAATQSNAFIKDIIDKKLSSTDNSSEPALIDRILNLVRIGELSY 279
            :    .|:||          |:|..:|...  |.||..|.|.|.:.:              |||.
Human   267 TDAVIQERRRTLTSQGVDDFLQAKAKSKTL--DFIDVLLLSEDKNGK--------------ELSD 315

  Fly   280 DDVMGEFSNIIFAASDTLSITVNNVLILMAMFPKYQDNVFEELAEVFPSGGEFEASHADLEKLVK 344
            :|:..|....:|...||.:..::.||..:|..|:||:...:|:.|:.......|....||.:|..
Human   316 EDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPF 380

  Fly   345 LDRVLHETMRLIPAVPLLIRQTSHSIQLSNGFYIPEGVTLMIDIFHTHRNKDIWGPQANAFNPDN 409
            |...|.|::||.|.:|...|..:..:.|.:...||:|....|:||..|.|..:| |....::|..
Human   381 LTMCLKESLRLHPPIPTFARGCTQDVVLPDSRVIPKGNVCNINIFAIHHNPSVW-PDPEVYDPFR 444

  Fly   410 FLPENKRARPPYSYLPFSKGKKTCLGWKLSLISAKLALAKILRNYML 456
            |.|||.:.|.|.:::|||.|.:.|:|.|.::...|:.||..|..:.:
Human   445 FDPENAQKRSPMAFIPFSAGPRNCIGQKFAMAEMKVVLALTLLRFRI 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a5	NP_650168.1	CYP313-like	65..482	CDD:410680	112/426 (26%)
CYP4F8	NP_009184.1	CYP4F	74..515	CDD:410772	116/437 (27%)