Protein Alignment Cyp313a5 and Cyp3a59

DIOPT Version :10

• Sequence 1: NP_650168.1
• Gene: Cyp313a5 / 41486
• FlyBaseID: FBgn0038005
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_001098630.1
• Gene: Cyp3a59 / 100041449
• MGIID: 3769707
• Length: 503
• Species: Mus musculus
• Alignment Length: 512
• Identity: 120/512 - (23%)
• Similarity: 218/512 - (42%)
• Gaps: 78/512 - (15%)

  Fly    12 IILCVYFLWSRRRFYIMMLKLPGPMGFPFIGLAFEYIRLKRKIRLRTILFKIYGKTVLTWIGLTP 76
            :...:|..:|...|  ..|.:|||...|..|..|.|  .....:.....:|.|||....::|..|
Mouse    20 VFFYIYGTYSHGLF--KKLGIPGPKPLPLFGTIFNY--FDGMWKFDEDCYKKYGKIWGFYVGPKP 80

  Fly    77 VLVTCEPKILE--------DIFTSPNCSNRSSVVDKAISSCLGLGLLTLKNNHWNERRKLLLPSF 133
            :|...:|:|::        .:||:.........:.|:|:        ..::..|...|.||.|:|
Mouse    81 ILAIMDPEIIKIVLVKECYSVFTNRPTLGPVGFLKKSIT--------ISEDEEWKRLRTLLSPTF 137

  Fly   134 KNNAVLSFVPVLNNEANFLV-TLLAEFVDGGDINLLPELNKWSFKIAAQITMGDEVRNQANYQNG 197
            .:..:....|::....:.|| .|..|...|..||:......:|..:....:.|..:.:..|.||.
Mouse   138 TSGKLKEMFPIMRQYGDILVRNLRREEEKGEPINMKDIFGAYSMDVITGTSFGVNIDSLNNPQNP 202

  Fly   198 NLLESYKALNNLIPIGVVMPWLRNKYLGKLFS--YEKRRLEAATQSN-----AFIKDIIDKKLSS 255
            .:.::.|    ::...:..|:|.:..|....:  ||...|....:.:     .|:|.:..::|:|
Mouse   203 FVQKTKK----ILKFKIFDPFLLSTILFPFLTPIYEMLNLSIFPRDSMNFFKKFVKRMKKERLAS 263

  Fly   256 --------------TDNS----SEPALIDRILNLVRIGELSYDDVMGEFSNIIFAASDTLSITVN 302
                          |.||    |:.||.|.        |::...|:     .||...|..|.:::
Mouse   264 KQKNRVDFLQLMMNTQNSKGQESQKALSDL--------EMAAQAVI-----FIFGGYDATSTSIS 315

  Fly   303 NVLILMAMFPKYQDNVFEELAEVFPSGGEFEASHADLEKLVKLDRVLHETMRLIPAVPLLIRQTS 367
            .::..:|..|..|..:.:|:....|:  :...::..|..:..||.|::|::||.|....|.|.:.
Mouse   316 LIMYELATHPDVQKKLQDEIDRTLPN--KAPVTYDALMDMEYLDMVVNESLRLYPTAIRLERVSK 378

  Fly   368 HSIQLSNGFYIPEGVTLMIDIFHTHRNKDIWGPQANAFNPDNFLPENKRARPPYSYLPFSKGKKT 432
            ..::: ||.:||:|..:||.|:..|||.:.| |:...|.|..|..||:....||.|:||..|.:.
Mouse   379 KDVEI-NGVFIPKGTVVMIPIYPLHRNPEYW-PEPQEFCPGRFSKENEGNIDPYIYMPFGNGPRN 441

  Fly   433 CLGWKLSLISAKLALAKILRNYMLSTTFLYKDLRFIDNT--TMKLAEQPLLAVKRRI 487
            ||..:.:|||.|||:..:|:|:.:..         .:.|  .:|::.:|:...::.|
Mouse   442 CLDMRFALISMKLAVIGVLQNFTVQP---------CEETQIPLKISREPVFQPEKPI 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a5	NP_650168.1	CYP313-like	65..482	CDD:410680	106/452 (23%)
Cyp3a59	NP_001098630.1	CYP3A	67..492	CDD:410743	108/461 (23%)