Protein Alignment Cyp313a5 and Cyp3a41b

DIOPT Version :10

• Sequence 1: NP_650168.1
• Gene: Cyp313a5 / 41486
• FlyBaseID: FBgn0038005
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_001098629.1
• Gene: Cyp3a41b / 100041375
• MGIID: 3714859
• Length: 504
• Species: Mus musculus
• Alignment Length: 526
• Identity: 131/526 - (24%)
• Similarity: 231/526 - (43%)
• Gaps: 82/526 - (15%)

  Fly     2 LTLQIFEAFAIILCVYFLWSRRRFYIMMLK-LPGPMGFPFIGLAFEYIRLKRKIRLRTILFKIYG 65
            |:|..:...||||.:.:.:..|...:...: :|||...||:|....|.:...|..:.  .::.||
Mouse     7 LSLDTWVLLAIILVLLYRYGTRTHGLFKKQGIPGPKPLPFLGTVLNYYKGLWKFDME--CYEKYG 69

  Fly    66 KTVLTWIGLTPVLVTCEPKILED--------IFTSPNCSNRSSVVDKAISSCLGLGLLTLKNNHW 122
            ||...:.|..|:.|..:|:::::        :||:........::.||||        ..|:..|
Mouse    70 KTWGLFDGQMPLFVITDPEMIKNVLVKECFSVFTNRREFGPVGIMSKAIS--------ISKDEEW 126

  Fly   123 NERRKLLLPSFKNNAVLSFVPVLNNEANFLVT-LLAEFVDGGDINLLPELNKWSFKIAAQITMGD 186
            ...|.||.|:|.:..:....||:....:.||. |:.|...|..:.:...|..:|..:....:.|.
Mouse   127 KRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQEAEKGKPVTMKDVLGAYSIDVITSTSFGV 191

  Fly   187 EVRNQANYQNGNLLESYKAL------NNLIPIGVVMPWLRNKY---------------------- 223
            .| :..|......:|..|.:      :.|:...|:.|:|...|
Mouse   192 NV-DSLNNPEDPFVEKAKGILRVDFFDPLVFSVVLFPFLTPVYEMLNICMFPKDSIEFFKKFVNR 255

  Fly   224 --LGKLFSYEKRRLEAATQSNAFIKDIIDKKLSSTDNSSEPALIDRILNLVRIGELSYDDVMGEF 286
              ..:|.|.:|.|::       |::.:::...:|.|..|..||.|.        |::...::
Mouse   256 MKESRLDSKQKHRVD-------FLQLMMNAHNNSKDKDSHKALSDM--------EITAQSIV--- 302

  Fly   287 SNIIFAASDTLSITVNNVLILMAMFPKYQDNVFEELAEVFPSGGEFEASHADLEKLVKLDRVLHE 351
              .|||..:|.|.|::..|..:|..|..|..:.||:.|..|:  :...::..:.::..||.||:|
Mouse   303 --FIFAGYETTSSTLSFTLYCLATHPDIQKKLQEEIDETLPN--KAPPTYDTVMEMEYLDMVLNE 363

  Fly   352 TMRLIPAVPLLIRQTSHSIQLSNGFYIPEGVTLMIDIFHTHRNKDIWGPQANAFNPDNFLPENKR 416
            |:||.|....|.|.....::| ||.|||:|.|:||..:..|.:...| |:...|.|:.|..|||.
Mouse   364 TLRLYPIGNRLERFCKKDVEL-NGVYIPKGSTVMIPSYALHHDPQHW-PEPEEFQPERFSKENKG 426

  Fly   417 ARPPYSYLPFSKGKKTCLGWKLSLISAKLALAKILRNYMLSTTFLYKDLRFIDNTTMKLAEQPLL 481
            :..||.|:||..|.:.|:|.:.:.::.||||.|:::|:.....   ::.:.    .:||:.|.||
Mouse   427 SIDPYLYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSFQPC---QETQI----PLKLSRQGLL 484

  Fly   482 AVKRRI 487
            ..::.|
Mouse   485 QPEKPI 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a5	NP_650168.1	CYP313-like	65..482	CDD:410680	113/455 (25%)
Cyp3a41b	NP_001098629.1	CYP3A	67..493	CDD:410743	116/464 (25%)