Protein Alignment CG3916 and KLK7

DIOPT Version :10

• Sequence 1: NP_650167.1
• Gene: CG3916 / 41484
• FlyBaseID: FBgn0038003
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_005037.1
• Gene: KLK7 / 5650
• HGNCID: 6368
• Length: 253
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 81/277 - (29%)
• Similarity: 130/277 - (46%)
• Gaps: 45/277 - (16%)

  Fly     1 MVVLQLFCMLLILRQGLADVVTSTTESPTRINGGQRVNETVPFQVSLQMQRRGRWQHFCGGSIVS 65
            ::.||:..:.|.|     :......:....|:|......:.|:||:|   ..|...| |||.:|:
Human     6 LLPLQILLLSLAL-----ETAGEEAQGDKIIDGAPCARGSHPWQVAL---LSGNQLH-CGGVLVN 61

  Fly    66 GQHVLTAAHCMEKMKVEDVSVVVG--TLNWKAGGLRHRLVTKHVHPQYSMNPRIINDIALVKVTP 128
            .:.|||||||    |:.:.:|.:|  ||..:. ..|.:......||.||.... :||:.|||:..
Human    62 ERWVLTAAHC----KMNEYTVHLGSDTLGDRR-AQRIKASKSFRHPGYSTQTH-VNDLMLVKLNS 120

  Fly   129 PFRLERSDISTILIGGSDRIGEKVPVR---------LTGWGSTSPSTSSATLPDQLQALNYRTIS 184
            ..||. |.:..:          ::|.|         ::|||:|  ::...|.|..|..::.:.||
Human   121 QARLS-SMVKKV----------RLPSRCEPPGTTCTVSGWGTT--TSPDVTFPSDLMCVDVKLIS 172

  Fly   185 NEDCNQKGFRVTRNE-ICA-LAVQGQGACVGDSGGPLIRPGKQPHLVGIVSYGSSTCAQ-GRPDV 246
            .:||.:....:..|. :|| :....:.||.|||||||:..|.   |.|:||:|:..|.| ..|.|
Human   173 PQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGT---LQGLVSWGTFPCGQPNDPGV 234

  Fly   247 YTRVSSFLPYISQVINQ 263
            ||:|..|..:|:..:.:
Human   235 YTQVCKFTKWINDTMKK 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3916	NP_650167.1	Tryp_SPc	30..257	CDD:214473	76/240 (32%)
KLK7	NP_005037.1	Tryp_SPc	29..245	CDD:214473	76/241 (32%)