Protein Alignment CG3916 and PLAT

DIOPT Version :10

• Sequence 1: NP_650167.1
• Gene: CG3916 / 41484
• FlyBaseID: FBgn0038003
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_000921.1
• Gene: PLAT / 5327
• HGNCID: 9051
• Length: 562
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 71/261 - (27%)
• Similarity: 124/261 - (47%)
• Gaps: 47/261 - (18%)

  Fly    30 RINGGQRVN-ETVPFQVSL-QMQRRGRWQHF-CGGSIVSGQHVLTAAHC-MEKMKVEDVSVVVGT 90
            ||.||...: .:.|:|.:: ...||...:.| |||.::|...:|:|||| .|:.....::|::|.
Human   310 RIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGR 374

  Fly    91 LNWKAGGLRHRLVTKHVHPQYSMNPRII----------NDIALVKV---TPPFRLERSDISTILI 142
                    .:|:|......::.:...|:          |||||:::   :.....|.|.:.|:.:
Human   375 --------TYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCL 431

  Fly   143 GGSD-RIGEKVPVRLTGWG---STSPSTSSATLPDQLQALNYRTISNEDCNQKGF---RVTRNEI 200
            ..:| ::.:.....|:|:|   :.||..|     ::|:..:.|...:..|..:..   .||.|.:
Human   432 PPADLQLPDWTECELSGYGKHEALSPFYS-----ERLKEAHVRLYPSSRCTSQHLLNRTVTDNML 491

  Fly   201 CALAVQGQG-------ACVGDSGGPLI--RPGKQPHLVGIVSYGSSTCAQGRPDVYTRVSSFLPY 256
            ||...:..|       ||.|||||||:  ..|:.. ||||:|:|.....:..|.|||:|:::|.:
Human   492 CAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMT-LVGIISWGLGCGQKDVPGVYTKVTNYLDW 555

  Fly   257 I 257
            |
Human   556 I 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3916	NP_650167.1	Tryp_SPc	30..257	CDD:214473	70/259 (27%)
PLAT	NP_000921.1	FN1	41..83	CDD:214494
		Important for binding to annexin A2	42..52
		EGF	86..117	CDD:394967
		KR	125..209	CDD:238056
		Kringle	215..296	CDD:395005
		Tryp_SPc	313..559	CDD:238113	69/258 (27%)