Protein Alignment CG3916 and KLK12

DIOPT Version :10

• Sequence 1: NP_650167.1
• Gene: CG3916 / 41484
• FlyBaseID: FBgn0038003
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 87/266 - (32%)
• Similarity: 127/266 - (47%)
• Gaps: 53/266 - (19%)

  Fly     4 LQLFCMLLILRQGLADVVTSTTESPTRINGGQRVNETVPFQVSLQMQRRGRWQHFCGGSIVSGQH 68
            |.:|.:|.:|  ||:...|     |...||.:....:.|:||.|......|    |||.::..:.
Human     3 LSIFLLLCVL--GLSQAAT-----PKIFNGTECGRNSQPWQVGLFEGTSLR----CGGVLIDHRW 56

  Fly    69 VLTAAHCMEK---MKVEDVSVVVGTLNWKAGGLRHR--LVTKHVHPQY-SMNPRIINDIALVKVT 127
            |||||||...   :::.:.|  :..|:| ...:||.  .||   ||.| ..:....:|:.|:::.
Human    57 VLTAAHCSGSRYWVRLGEHS--LSQLDW-TEQIRHSGFSVT---HPGYLGASTSHEHDLRLLRLR 115

  Fly   128 PPFRLERS--------DISTILIGGSDRIGEKVPVRLTGWGSTSPSTSSATLPDQLQALNYRTIS 184
            .|.|:..|        |.:|   .|::       ..::|||.|:...:  ..||.||.||...:|
Human   116 LPVRVTSSVQPLPLPNDCAT---AGTE-------CHVSGWGITNHPRN--PFPDLLQCLNLSIVS 168

  Fly   185 NEDCNQKGF---RVTRNEICALAVQGQGACVGDSGGPLIRPGKQPHLVGIVSYGS-STCAQ-GRP 244
            :..|:  |.   |:|.|.:||..|.||.||.|||||||:..|.   |.|:||:|| ..|.| |.|
Human   169 HATCH--GVYPGRITSNMVCAGGVPGQDACQGDSGGPLVCGGV---LQGLVSWGSVGPCGQDGIP 228

  Fly   245 DVYTRV 250
            .|||.:
Human   229 GVYTYI 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3916	NP_650167.1	Tryp_SPc	30..257	CDD:214473	79/240 (33%)
KLK12	NP_062544.1	Tryp_SPc	22..236	CDD:238113	79/240 (33%)