Protein Alignment CG3916 and KLK14

DIOPT Version :10

• Sequence 1: NP_650167.1
• Gene: CG3916 / 41484
• FlyBaseID: FBgn0038003
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_071329.3
• Gene: KLK14 / 43847
• HGNCID: 6362
• Length: 251
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 87/268 - (32%)
• Similarity: 134/268 - (50%)
• Gaps: 37/268 - (13%)

  Fly     9 MLLILRQGLADVVTSTTESPTRINGGQR-VNETVPFQVSLQMQRRGRWQHFCGGSIVSGQHVLTA 72
            :||...|.||..:|.:.|...:|.||.. ...:.|:|.:|....|.|:  .|||:::|||.|:||
Human     3 LLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRF--LCGGALLSGQWVITA 65

  Fly    73 AHCMEKMKVEDVSVVVGTLN---WKAGGLRHRLVTKHVHPQYSMNPRIINDIALVKVTPPFRLER 134
            |||...:    :.|.:|..|   |:|.....|:|.:..||.|:.... .||:.|:::..|.|:.|
Human    66 AHCGRPI----LQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTH-DNDLMLLQLQQPARIGR 125

  Fly   135 SDISTILI-------GGSDRIGEKVPVRLTGWGSTSPSTSSATLPDQLQALNYRTISNEDCNQKG 192
            : :..|.:       |.|        .|::|||:.  |:..|..|..||.:|.....:|.| ||.
Human   126 A-VRPIEVTQACASPGTS--------CRVSGWGTI--SSPIARYPASLQCVNINISPDEVC-QKA 178

  Fly   193 F--RVTRNEICALAVQ-GQGACVGDSGGPLIRPGKQPHLVGIVSYGSSTCA-QGRPDVYTRVSSF 253
            :  .:|...:||...| |:.:|.|||||||:..|:   |.|:||:|...|| .|.|.|||.:..:
Human   179 YPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQ---LQGLVSWGMERCALPGYPGVYTNLCKY 240

  Fly   254 LPYISQVI 261
            ..:|.:.:
Human   241 RSWIEETM 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3916	NP_650167.1	Tryp_SPc	30..257	CDD:214473	79/241 (33%)
KLK14	NP_071329.3	Tryp_SPc	25..247	CDD:238113	80/243 (33%)