Protein Alignment CG3916 and KLK2

DIOPT Version :10

• Sequence 1: NP_650167.1
• Gene: CG3916 / 41484
• FlyBaseID: FBgn0038003
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 76/250 - (30%)
• Similarity: 119/250 - (47%)
• Gaps: 32/250 - (12%)

  Fly    29 TRINGGQRVNE-TVPFQVSLQMQRRGRWQHFCGGSIVSGQHVLTAAHCMEKMKVEDVSVVVGTLN 92
            :||.||....: :.|:||::...   .|.| |||.:|..|.|||||||::|    :..|.:|..|
Human    23 SRIVGGWECEKHSQPWQVAVYSH---GWAH-CGGVLVHPQWVLTAAHCLKK----NSQVWLGRHN 79

  Fly    93 -WKAGGLRHRLVTKH--VHPQYSM----------NPRIINDIALVKVTPPFRLERSDISTILIGG 144
             ::......|:...|  .||.|:|          :....:|:.|::::.|.::  :|:..:|...
Human    80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKI--TDVVKVLGLP 142

  Fly   145 SDRIGEKVPVRLTGWGSTSPSTSSATLPDQLQALNYRTISNEDCNQK-GFRVTRNEICA-LAVQG 207
            :...........:||||..|  .....|..||.::...:||:.|.:. ..:||...:|| |...|
Human   143 TQEPALGTTCYASGWGSIEP--EEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGG 205

  Fly   208 QGACVGDSGGPLIRPGKQPHLVGIVSYGSSTCA-QGRPDVYTRVSSFLPYISQVI 261
            :..|.|||||||:..|.   |.||.|:|...|| ..:|.|||:|..:..:|...|
Human   206 KDTCGGDSGGPLVCNGV---LQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3916	NP_650167.1	Tryp_SPc	30..257	CDD:214473	74/243 (30%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	74/245 (30%)