Protein Alignment CG3916 and KLK3

DIOPT Version :10

• Sequence 1: NP_650167.1
• Gene: CG3916 / 41484
• FlyBaseID: FBgn0038003
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_001639.1
• Gene: KLK3 / 354
• HGNCID: 6364
• Length: 261
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 88/287 - (30%)
• Similarity: 128/287 - (44%)
• Gaps: 56/287 - (19%)

  Fly     1 MVVLQLFCMLLILRQGLADVVTSTTESPTRINGGQRVNE-TVPFQVSLQMQRRGRWQHFCGGSIV 64
            |.|..:|..|.:...|.|.::.|      ||.||....: :.|:||  .:..|||  ..|||.:|
Human     1 MWVPVVFLTLSVTWIGAAPLILS------RIVGGWECEKHSQPWQV--LVASRGR--AVCGGVLV 55

  Fly    65 SGQHVLTAAHCMEKMKVEDVSVVVGTLNWKAGGLRHRLV----TKHV--------HPQYSMN--- 114
            ..|.|||||||:....|    :::|         ||.|.    |..|        ||.|.|:
Human    56 HPQWVLTAAHCIRNKSV----ILLG---------RHSLFHPEDTGQVFQVSHSFPHPLYDMSLLK 107

  Fly   115 PRII-------NDIALVKVTPPFRLERSDISTILIGGSDRIGEKVPVRLTGWGSTSPSTSSATLP 172
            .|.:       :|:.|::::.|  .|.:|...::...:...........:||||..|  .....|
Human   108 NRFLRPGDDSSHDLMLLRLSEP--AELTDAVKVMDLPTQEPALGTTCYASGWGSIEP--EEFLTP 168

  Fly   173 DQLQALNYRTISNEDCNQ-KGFRVTRNEICA-LAVQGQGACVGDSGGPLIRPGKQPHLVGIVSYG 235
            .:||.::...|||:.|.| ...:||:..:|| ....|:..|.|||||||:..|.   |.||.|:|
Human   169 KKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGV---LQGITSWG 230

  Fly   236 SSTCA-QGRPDVYTRVSSFLPYISQVI 261
            |..|| ..||.:||:|..:..:|...|
Human   231 SEPCALPERPSLYTKVVHYRKWIKDTI 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3916	NP_650167.1	Tryp_SPc	30..257	CDD:214473	79/252 (31%)
KLK3	NP_001639.1	Tryp_SPc	25..256	CDD:238113	79/254 (31%)