Protein Alignment CG3916 and HGFAC

DIOPT Version :10

• Sequence 1: NP_650167.1
• Gene: CG3916 / 41484
• FlyBaseID: FBgn0038003
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_001284368.1
• Gene: HGFAC / 3083
• HGNCID: 4894
• Length: 662
• Species: Homo sapiens
• Alignment Length: 301
• Identity: 78/301 - (25%)
• Similarity: 125/301 - (41%)
• Gaps: 74/301 - (24%)

  Fly    19 DVVTSTTESPTRINGGQRVNETVPFQVSLQMQRRGR------------------------W---- 55
            |:.|...||.||:.....:..|:|...|...|..||                        |
Human   368 DLETEGRESLTRVQLSPDLLATLPEPASPGRQACGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAI 432

  Fly    56 ---QHFCGGSIVSGQHVLTAAHCMEKMKVED-VSVVVGT--LNWKAGGLRHRLVTKHV-HPQYSM 113
               ..||.||:|....|::||||.......| ||||:|.  .|......:...:.|:: :..||:
Human   433 YIGDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSV 497

  Fly   114 -NPRIINDIALVKVTPPFRLERSD--------ISTILI---GGSDRIGEKVPVRLTGWGSTSPST 166
             ||. .:|:.|:::.     ::.|        :..|.:   |.:...|.|  .::.|||....:.
Human   498 FNPS-DHDLVLIRLK-----KKGDRCATRSQFVQPICLPEPGSTFPAGHK--CQIAGWGHLDENV 554

  Fly   167 S--SATLPDQLQALNYRTISNEDCNQK---GFRVTRNEICALAVQG-----QGACVGDSGGPL-I 220
            |  |::|.:.|..|    :::..|:..   |..::.|.:||    |     ..||.||||||| .
Human   555 SGYSSSLREALVPL----VADHKCSSPEVYGADISPNMLCA----GYFDCKSDACQGDSGGPLAC 611

  Fly   221 RPGKQPHLVGIVSYGSSTCAQGRPDVYTRVSSFLPYISQVI 261
            ......:|.||:|:|.......:|.|||||::::.:|:..|
Human   612 EKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRI 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3916	NP_650167.1	Tryp_SPc	30..257	CDD:214473	71/284 (25%)
HGFAC	NP_001284368.1	PRK14954	<32..>100	CDD:184918
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	64..102
		FN2	102..148	CDD:128373
		EGF_CA	162..197	CDD:238011
		FN1	200..240	CDD:238018
		EGF_CA	245..278	CDD:238011
		Kringle	286..367	CDD:395005
		Tryp_SPc	415..650	CDD:238113	65/250 (26%)