DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Su(var)3-9 and SET2

DIOPT Version :9

Sequence 1:	NP_524357.2	Gene:	Su(var)3-9 / 41483	FlyBaseID:	FBgn0263755	Length:	635	Species:	Drosophila melanogaster
Sequence 2:	NP_012367.2	Gene:	SET2 / 853271	SGDID:	S000003704	Length:	733	Species:	Saccharomyces cerevisiae

Alignment Length:	228	Identity:	66/228 - (28%)
Similarity:	97/228 - (42%)	Gaps:	49/228 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   412 CKCTEDTEE-----CTASTKCCARFAGELFAYERSTRRLRLRPGSAIYEC-NSRC-SCDSSCSNR 469
            |.|.|:..:     |...:.|..|.                    .:.|| |..| ||.:.|.|:
Yeast    68 CDCYEEFSDGVNHACDEDSDCINRL--------------------TLIECVNDLCSSCGNDCQNQ 112

  Fly   470 LVQHGRQVPLVLFKTANGSGWGVRAATALRKGEFVCEYIGEIITSDEANERGKAYDDNGRTYLFD 534
            ..|..:..|:.:|||.: .|:||||...:...:|:.||.||:|...|..:|...||.....:.:
Yeast   113 RFQKKQYAPIAIFKTKH-KGYGVRAEQDIEANQFIYEYKGEVIEEMEFRDRLIDYDQRHFKHFY- 175

  Fly   535 LDYNTAQDSEYTIDAANYGNISHFINHSCDPNLAVFPCWI--EHLNVALPHLVFFTLRPIKAGEE 597
              :...|:.|: |||...|:::.|.||||.|| |....|:  :.|.:.:     |..|.|..|||
Yeast   176 --FMMLQNGEF-IDATIKGSLARFCNHSCSPN-AYVNKWVVKDKLRMGI-----FAQRKILKGEE 231

  Fly   598 LSFDYIRADNEDVPYENLSTAVRVECRCGADNC 630
            ::|||    |.|     ...|...:|.|...||
Yeast   232 ITFDY----NVD-----RYGAQAQKCYCEEPNC 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-9	NP_524357.2	P-loop_NTPase	41..>80	CDD:304359
		CHROMO	217..268	CDD:237991
		PreSET	362..455	CDD:128744	6/47 (13%)
		SET	477..609	CDD:214614	45/133 (34%)
SET2	NP_012367.2	AWS	64..119	CDD:197795	15/70 (21%)
		SET_SETD2	119..260	CDD:380949	51/157 (32%)
		SET	215..695	CDD:225491	17/55 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910