Protein Alignment Su(var)3-9 and Kmt5a

DIOPT Version :10

• Sequence 1: NP_524357.2
• Gene: Su(var)3-9 / 41483
• FlyBaseID: FBgn0263755
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: XP_036021341.1
• Gene: Kmt5a / 67956
• MGIID: 1915206
• Length: 372
• Species: Mus musculus
• Alignment Length: 344
• Identity: 82/344 - (23%)
• Similarity: 135/344 - (39%)
• Gaps: 86/344 - (25%)

  Fly   292 PLMENITVAEVDAY---EPLNLQIDLILLAQYRAAGSRSQREPQK----IGERALKSMQIKRAQF 349
            ||.|..:||..:..   :||              ||...:||.::    :...|:||.: ::::.
Mouse    89 PLQEENSVAHHEVKCPGKPL--------------AGIYRKREEKRNTGNVIRSAVKSDE-QKSKD 138

  Fly   350 VRRKQLADLALFEKRMNHVEKP--SPPIRVENNIDLDTIDSNFMYIHDNIIGKDVPKPEAGIVGC 412
            .||   ..||.|..:.:...:|  :||    .:.|...:......:..::.||..|:.
Mouse   139 TRR---GPLAPFPNQKSEAAEPPKTPP----PSCDSTNVAVAKQALKKSLKGKQAPRK------- 189

  Fly   413 KCTEDTEECTASTKCCARFAGELFAYERSTRRLRLRPGSAIYECNSRCSCDSSCSNRLVQHGRQ- 476
            |....|::....|        :.:...||:|:     ..|..:...|...|     .|::.|::
Mouse   190 KSQGKTQQNRKLT--------DFYPVRRSSRK-----SKAELQSEERKKID-----ELIESGKEE 236

  Fly   477 ---VPLVLFKTANGSGWGVRAATALRKGEFVCEYIGEIITSDEANERGKAY--DDNGRTYLFDLD 536
               :.|:     :|.|.||.|.....:|:||.||.|::|...:|.:|...|  |.:...|::...
Mouse   237 GMKIDLI-----DGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQ 296

  Fly   537 YNTAQDSEYTIDAANYGN-ISHFINHS----CDPNLAVFPCWIEHLNVALPHLVFFTLRPIKAGE 596
            |   ....|.:||....| :...||||    |...|        |....:|||:....|.|.|||
Mouse   297 Y---LSKTYCVDATQETNRLGRLINHSKCGNCQTKL--------HDIDGVPHLILIASRDIAAGE 350

  Fly   597 ELSFDY---IRADNEDVPY 612
            ||.:||   .:|..|..|:
Mouse   351 ELLYDYGDRSKASIEAYPW 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-9	NP_524357.2	PTZ00327	11..>80	CDD:240362
		Chromo	219..268	CDD:459793
		SET_SUV39H	388..634	CDD:380940	59/239 (25%)
Kmt5a	XP_036021341.1	PLN02543	147..>241	CDD:215299	19/122 (16%)
		SET_SETD8	220..359	CDD:380926	46/159 (29%)