back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Su(var)3-9 and Suv39h2

DIOPT Version :9

Sequence 1:	NP_524357.2	Gene:	Su(var)3-9 / 41483	FlyBaseID:	FBgn0263755	Length:	635	Species:	Drosophila melanogaster
Sequence 2:	NP_073561.2	Gene:	Suv39h2 / 64707	MGIID:	1890396	Length:	477	Species:	Mus musculus

Alignment Length:	548	Identity:	182/548 - (33%)
Similarity:	268/548 - (48%)	Gaps:	130/548 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 RRHSRFRRLCTKPASSSMPASTSSVDRRTTRRSTSQTSLSPSNSSGYGSVFG--CEEHDVDK--- 175
            ||.:|.||..|..|..|.|::..       ||:.||.:.|   .:...:|||  |....:.|
Mouse    30 RRTARRRRAETLTARRSRPSAGE-------RRAGSQRAWS---GAPRAAVFGDECARGALFKAWC 84

  Fly   176 IP---SLNGFAKL-KRRRSSC--VGAPTPNSKRSKNNMGVIAKRPPKGEYVVERIECVEMDQYQP 234
            :|   ||:...:| ::.:.:|  :|.    :||:.||..|        ||:.:......::.|
Mouse    85 VPCLVSLDTLQELCRKEKLTCKSIGI----TKRNLNNYEV--------EYLCDYKVAKGVEYY-- 135

  Fly   235 VFFVKWLGYHDSENTWESLANVADCAEMEKFVERHQQLYEIYIAKITTELEKQLEALPLMENITV 299
              .|||.|:.||.||||.|.|:. |.::.:.....::.|
Mouse   136 --LVKWKGWPDSTNTWEPLRNLR-CPQLLRQFSDDKKTY-------------------------- 171

  Fly   300 AEVDAYEPLNLQIDLILLAQYRAAGSRSQREPQKIGERALKSMQIKRAQFVRRKQLADLAL---- 360
                             |||.|...:.:.           ||:|...|:::.:|....:||
Mouse   172 -----------------LAQERKCKAVNS-----------KSLQPAIAEYIVQKAKQRIALQRWQ 208

  Fly   361 --FEKRMNHVEKPSPPIRVENNIDLDTIDSNFMYIHDNIIGKDVPKPEAGI-------VGCKCTE 416
              ..:|.||    ...|.|||.:||:....:|.||::.       :|..||       .||.||
Mouse   209 DYLNRRKNH----KGMIFVENTVDLEGPPLDFYYINEY-------RPAPGISINSEATFGCSCT- 261

  Fly   417 DTEECTASTKCCARFAGELFAYERSTRRLRLRPGSAIYECNSRCSCDSSCSNRLVQHGRQVPLVL 481
               :|... |||...||.:.||.:. ::::::||:.||||||||.|...|.||:||.|.|..|.:
Mouse   262 ---DCFFD-KCCPAEAGVVLAYNKK-QQIKIQPGTPIYECNSRCRCGPECPNRIVQKGTQYSLCI 321

  Fly   482 FKTANGSGWGVRAATALRKGEFVCEYIGEIITSDEANERGKAYDDNGRTYLFDLDYNTAQDSEYT 546
            |:|:||.||||:....:::..||.||:||:|||:||..||:.||:.|.||||||||   :..|:|
Mouse   322 FRTSNGCGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDY---ESDEFT 383

  Fly   547 IDAANYGNISHFINHSCDPNLAVFPCWIEHLNVALPHLVFFTLRPIKAGEELSFDYI-----RAD 606
            :|||.|||:|||:||||||||.||..:|::|:..||.:..|:.|.|.|||||:|||.     .|.
Mouse   384 VDAARYGNVSHFVNHSCDPNLQVFSVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGEAS 448

  Fly   607 NEDVPYENLSTAVRVECRCGADNCRKVL 634
            ::.:.:......||.:|:|||:.||..|
Mouse   449 SDSIDHSPAKKRVRTQCKCGAETCRGYL 476

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.