Protein Alignment Su(var)3-9 and KLK7

DIOPT Version :10

• Sequence 1: NP_524357.2
• Gene: Su(var)3-9 / 41483
• FlyBaseID: FBgn0263755
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_005037.1
• Gene: KLK7 / 5650
• HGNCID: 6368
• Length: 253
• Species: Homo sapiens
• Alignment Length: 219
• Identity: 42/219 - (19%)
• Similarity: 70/219 - (31%)
• Gaps: 57/219 - (26%)

  Fly    25 SKLTPLSPEVISRQATINIGTIGHVAHGKSTV-------------VKAISG-------------- 62
            |.|.||...::|    :.:.|.|..|.|...:             |..:||
Human     4 SLLLPLQILLLS----LALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERW 64

  Fly    63 VQTVRFKNELERNITIKLERLSEKKIKNLLTSKQQRQQ-YEIKQRSMLRHLAELRRHSRFRRLCT 126
            |.|.......|..:.:..:.|.:::.:.:..||..|.. |..:.......|.:|...:|...:..
Human    65 VLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVK 129

  Fly   127 K---PASSSMPASTSSVDRRTTRRSTSQTSLSPSNSSGYGSVFGCEE------HDVDKIPSLNGF 182
            |   |:....|.:|.:|....|..|...|         :.|...|.:      .|..|:     :
Human   130 KVRLPSRCEPPGTTCTVSGWGTTTSPDVT---------FPSDLMCVDVKLISPQDCTKV-----Y 180

  Fly   183 AKLKRRRSSCVGAPTPNSKRSKNN 206
            ..|......|.|  .|:||::..|
Human   181 KDLLENSMLCAG--IPDSKKNACN 202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-9	NP_524357.2	PTZ00327	11..>80	CDD:240362	15/81 (19%)
		Chromo	219..268	CDD:459793
		SET_SUV39H	388..634	CDD:380940
KLK7	NP_005037.1	Tryp_SPc	29..245	CDD:214473	33/190 (17%)