DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Su(var)3-9 and setmar

DIOPT Version :9

Sequence 1:	NP_524357.2	Gene:	Su(var)3-9 / 41483	FlyBaseID:	FBgn0263755	Length:	635	Species:	Drosophila melanogaster
Sequence 2:	NP_001107072.1	Gene:	setmar / 564575	ZFINID:	ZDB-GENE-080204-61	Length:	293	Species:	Danio rerio

Alignment Length:	284	Identity:	95/284 - (33%)
Similarity:	135/284 - (47%)	Gaps:	45/284 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   374 PIRVENNIDLDTIDSNFMYIHDNIIGK--DVPKPEAGIVGCKCTEDTEECTASTKCCARFAGELF 436
            |:.:||::..:.: |.|.|:.:|:.|.  |:......:.||.|.  .:.|......|.|| |:.:
Zfish    16 PVLIENSVPKEAL-SYFQYVPENVQGPGCDLDPNAVTLPGCSCR--VQSCFPERCPCLRF-GQTY 76

  Fly   437 AYERSTRRLRLRPGSA-----IYECNSRCSCDSSCSNRLVQHGRQVPLVLFKTANGSGWGVRAAT 496
               .|...|...|..|     ::|||:.|||..||..|:||:|..|.|.:|.||: .|.||.|..
Zfish    77 ---DSRACLNQHPQDATYSRPVFECNAFCSCGESCQTRVVQNGVCVRLGVFSTAD-RGLGVEALE 137

  Fly   497 ALRKGEFVCEYIGEIITSDEANERGKAYDDNGRTYLFDLDYNTAQD--SEYTIDAANYGNISHFI 559
            .|..|.|||||.||:|..|||..|..:.......|:..:..:...|  ::..:|..|.||:..||
Zfish   138 RLPCGRFVCEYAGEVIGIDEARRRQLSQTPLHMNYIIAVQEHKGLDRVTQTFVDPVNLGNVGRFI 202

  Fly   560 NHSCDPNLAVFPCWIEHLNVALPHLVFFTLRPIKAGEELSFDY------------------IRAD 606
            ||||.|||.:.|.   .::..||.|..|..|.|:..|||:|||                  :.||
Zfish   203 NHSCQPNLIMLPV---RVHSVLPRLALFANRDIECYEELTFDYSGGQNSSAETAKLDEETHVGAD 264

  Fly   607 NEDVPYENLSTAVRVECRCGADNC 630
            .|::|.:.:       |||||.||
Zfish   265 GEEIPQKKV-------CRCGASNC 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-9	NP_524357.2	P-loop_NTPase	41..>80	CDD:304359
		CHROMO	217..268	CDD:237991
		PreSET	362..455	CDD:128744	21/87 (24%)
		SET	477..609	CDD:214614	53/151 (35%)
setmar	NP_001107072.1	Pre-SET	8..111	CDD:282838	29/101 (29%)
setmar	NP_001107072.1	SET	119..243	CDD:214614	50/127 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D753093at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820