Protein Alignment Su(var)3-9 and Set2

DIOPT Version :10

• Sequence 1: NP_524357.2
• Gene: Su(var)3-9 / 41483
• FlyBaseID: FBgn0263755
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: XP_061511250.1
• Gene: Set2 / 4577900
• VectorBaseID: AGAMI1_014733
• Length: 2662
• Species: Anopheles gambiae
• Alignment Length: 618
• Identity: 145/618 - (23%)
• Similarity: 227/618 - (36%)
• Gaps: 154/618 - (24%)

  Fly    26 KLTPLSPEVISRQATINIGTIGHVAHGKSTVVKAISGVQTVRFKNELERNITIKLERLSEKKIKN 90
            ::||.:.|:             ||:....|.|.            ||...:.:|.|..:......
Mosquito  1096 QVTPKAEEI-------------HVSEVVQTKVA------------ELPTQLPVKEEPPATLDAVP 1135

  Fly    91 LLTSKQQRQQYEIKQRSMLRHLAELRRHSRFRRLCTKPASSSMPASTSSVDRRTTRRSTSQTSLS 155
            .:..|.:.||           ||||:....|                |..:   |.||.|...||
Mosquito  1136 PMEPKPETQQ-----------LAELKEEEAF----------------SDAE---TLRSDSVAGLS 1170

  Fly   156 PSN--------SSGYGSVFGCEEHDVDKIPSLNGFAKLKRRRSSCVGAPTPNSKRSKNNMGVIAK 212
            .|.        |||:.|     |.|    ..:...|.......|| ..|.|.|.....::.|:
Mosquito  1171 DSEGLSAPSRCSSGFPS-----EDD----SGVRSGASTPYDLMSC-DEPDPASSGGGGSVTVV-- 1223

  Fly   213 RPPKGEYVVERIECVEMDQYQPVFFVKWLGYHDSENTWESLANVADCAEMEKFVERHQQLYEIYI 277
             ||.....||.:...:.|. |.|..|:.:..:..:........:...:..::....|
Mosquito  1224 -PPSSVPSVEEVRDEDRDS-QRVDMVRLVESYIDDGVIRRSTRIKTISSQKQRTSGH-------- 1278

  Fly   278 AKITTELEKQLEALPLMENITVAEVDAYEPLNLQIDLILLAQYRAAGSRSQREPQKIGERALKSM 342
             .:..:.:|      ||:..:.|..|||.          .|:..|.|..:.....:.|.....:.
Mosquito  1279 -GLVRDRDK------LMKKSSGAVGDAYG----------TAEALAGGYSASEMAMQSGGHLQGAA 1326

  Fly   343 QIKRAQF---VRRKQLADLALFEKRMNHVEKPSPPIRVENNIDLDTIDSNFMYIHDNIIGKDVPK 404
            .:....:   ......|::.|.|:.:..:|        |.....:||..| :|..|.|:.::..|
Mosquito  1327 GVSGPAWPVIANEGDSANVELSEEYLRDME--------EKLSRFETIREN-IYHSDRIVSREAKK 1382

  Fly   405 PEAGIVGCKCTEDTEECTASTKCCARFAGELFAYERSTRRLRLRPGSAIYECNSRCSCDSSCSNR 469
                 :.|.|....||.......|.         |....||      .:.||.|||:....|:||
Mosquito  1383 -----MTCDCFLTHEEIERGEHGCG---------EDCLNRL------LMIECGSRCTVGDRCTNR 1427

  Fly   470 LVQHGRQVPLVLFKTANGSGWGVRAATALRKGEFVCEYIGEIITSDEANERGKAYD-DNGRTYLF 533
            ..|........:|:|.. .|:|::|::|:..|||:.||:||::.|.:.:||.:||. :..:.|.|
Mosquito  1428 RFQRQEYAHCQVFRTEK-KGFGIQASSAIAPGEFIMEYVGEVLNSAQFDERAEAYSREKNKHYYF 1491

  Fly   534 DLDYNTAQDSEYTIDAANYGNISHFINHSCDPNLAVFPCWIEHLNVALPHLVFFTLRPIKAGEEL 598
                 .|..|:..|||...||||.||||||||| |....|.  :|..| .:.||:.:.|..|||:
Mosquito  1492 -----MALRSDGIIDATTKGNISRFINHSCDPN-AETQKWT--VNGEL-RIGFFSTKYILPGEEI 1547

  Fly   599 SFDYIRADNEDVPYENLSTAVRVECRCGADNCR 631
            :|||        .::......: :|.|.|::||
Mosquito  1548 TFDY--------QFQRYGRKAQ-KCYCEAESCR 1571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-9	NP_524357.2	PTZ00327	11..>80	CDD:240362	9/53 (17%)
		Chromo	219..268	CDD:459793	6/48 (13%)
		SET_SUV39H	388..634	CDD:380940	78/245 (32%)
Set2	XP_061511250.1	None