Protein Alignment Su(var)3-9 and ash1

DIOPT Version :10

• Sequence 1: NP_524357.2
• Gene: Su(var)3-9 / 41483
• FlyBaseID: FBgn0263755
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_524160.2
• Gene: ash1 / 40133
• FlyBaseID: FBgn0005386
• Length: 2226
• Species: Drosophila melanogaster
• Alignment Length: 756
• Identity: 153/756 - (20%)
• Similarity: 256/756 - (33%)
• Gaps: 203/756 - (26%)

  Fly    18 DLSNLDVSKLTPLSPEVISRQATINIGTIGHVAHGKSTVVKAISGVQTVR--------FKNELER 74
            |.:::...||..:||   |...::.....|..|..|.:..|.:..:|:..        |:..:|.
  Fly   838 DNNSISGGKLLDISP---SSLCSLKQQRRGGAAKQKVSAAKDLVQLQSPAGSYPPPGVFEPSVEL 899

  Fly    75 NITIKLERLSEKKIKNLLTSKQQRQQYEIKQ---RSMLRHLAELRRHSRFRRLCTKPASSSMPAS 136
            .|.|.|.:|:|..|.............:||:   :.:.:.:.|...|.....|..|.....:..:
  Fly   900 EIQIPLSKLNESVITKAEVESPLLSALDIKEDTKKEVGQRVVETLLHKTGGNLLLKRKRKKINRT 964

  Fly   137 TSSVDRRTTRRST--SQT-------------------SLSPSNSSGYGSVFGCEEHDVD------ 174
            .....||..|:.:  .||                   ||..:.||...:|.......:|
  Fly   965 GFPTVRRKKRKVSVEQQTTAVIDEHEPEFDPDDEPLQSLRETRSSNNVNVQAAPNPPLDCERVPQ 1029

  Fly   175 --------------KIPSLNGFA--KLKRRRSSCVGAPTPNSKRSKNNMGVIAKRPPKGEYVVER 223
                          |.|.|:..|  :|:|.::...|.|.....:::.......:.|||.|..:..
  Fly  1030 AGEARETFVARTNQKAPRLSVVALERLQRPQTPARGRPRGRKPKNREQAEAAPQPPPKSEPEIRP 1094

  Fly   224 IECVEMDQYQPVFFVKWLGYHDSENTWESLANVADCAEMEKFVERHQQLYE------IYIAKITT 282
            .:.......|||.              |.........:.:..:|.:.:|.:      .:..||..
  Fly  1095 AKKRGRQPKQPVL--------------EEPPPTPPPQQKKNKMEPNIRLPDGIDPNTNFSCKIRL 1145

  Fly   283 ELEKQLEA---------------------LPLMENITVAEVDA--YEPLNLQIDLILLAQYRAAG 324
            :..|.|||                     :|:.:....||.:|  .:.:..:.|.:..::....|
  Fly  1146 KRRKNLEAGTQPKKEKPVQPVTVEEIPPEIPVSQEEIDAEAEAKRLDSIPTEHDPLPASESHNPG 1210

  Fly   325 SRSQREPQKIGERALKSMQIKRAQFVRRKQLADLALFEKRMNHVEK------------------- 370
            .:......:..|....:..:::...|::..|. ..||.   ||.::
  Fly  1211 PQDYASCSESSEDKASTTSLRKLSKVKKTYLV-AGLFS---NHYKQSLMPPPAKVNKKPGLEEQV 1271

  Fly   371 ------PSPPI------RVENNIDL----------------DTIDS-NFMYIHDNIIGKDVPKPE 406
                  |.||.      |.|.:.:|                :.:.| |:..|..|:..:.|....
  Fly  1272 GPASLLPPPPYCEKYLRRTEMDFELPYDIWWAYTNSKLPTRNVVPSWNYRKIRTNVYAESVRPNL 1336

  Fly   407 AGIVGCKCTEDTEECTASTKCCARFAGELFAYERSTRRLRLRPGSAIY-ECN-SRCSCDSSCSNR 469
            ||.       |...|....:      ||....:....|:       :| ||: |.|.....|.|:
  Fly  1337 AGF-------DHPTCNCKNQ------GEKSCLDNCLNRM-------VYTECSPSNCPAGEKCRNQ 1381

  Fly   470 LVQHGRQVPLV-LFKTANGSGWGVRAATALRKGEFVCEYIGEIITSDEANER-GKAYDDNGRTYL 532
            .:|.....|.| .|.||: .|||||....:.||.::.||:||::|..|..:| ...|.::...|.
  Fly  1382 KIQRHAVAPGVERFMTAD-KGWGVRTKLPIAKGTYILEYVGEVVTEKEFKQRMASIYLNDTHHYC 1445

  Fly   533 FDLDYNTAQDSEYTIDAANYGNISHFINHSCDPNLAVFPCWIEHLNV-ALPHLVFFTLRPIKAGE 596
            ..|      |....||....|:...|:||||:||     |.::..:| .|..:|.|..|.|:.||
  Fly  1446 LHL------DGGLVIDGQRMGSDCRFVNHSCEPN-----CEMQKWSVNGLSRMVLFAKRAIEEGE 1499

  Fly   597 ELSFDY---IRADNEDVPYENLSTAVRVECRCGADNCRKVL 634
            ||::||   :...:|..|           |||....||.|:
  Fly  1500 ELTYDYNFSLFNPSEGQP-----------CRCNTPQCRGVI 1529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-9	NP_524357.2	PTZ00327	11..>80	CDD:240362	15/69 (22%)
		Chromo	219..268	CDD:459793	4/48 (8%)
		SET_SUV39H	388..634	CDD:380940	73/254 (29%)
ash1	NP_524160.2	PHA03247	<1018..1281	CDD:223021	39/280 (14%)
		AWS	1340..1388	CDD:197795	13/60 (22%)
		SET_ASH1L	1391..1531	CDD:380951	53/162 (33%)
		Bromo_ASH1	1680..1787	CDD:99955
		PHD_ASH1L	1858..1900	CDD:277023
		BAH_polybromo	1929..2073	CDD:240068