Protein Alignment Su(var)3-9 and Ash1l

DIOPT Version :10

• Sequence 1: NP_524357.2
• Gene: Su(var)3-9 / 41483
• FlyBaseID: FBgn0263755
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: XP_063137913.1
• Gene: Ash1l / 310638
• RGDID: 1306350
• Length: 3000
• Species: Rattus norvegicus
• Alignment Length: 615
• Identity: 135/615 - (21%)
• Similarity: 230/615 - (37%)
• Gaps: 189/615 - (30%)

  Fly   128 PASSSMPASTSSVDRRTTRRSTSQTSLSPSNSSGYGSVFG------CEEHDV------------- 173
            |.||| |..:.|.:|...:..:......||:|.....:..      |..|.:
  Rat  1783 PPSSS-PGHSYSKERTLGKSDSLLVPAVPSDSCNSIPLLSEKLASRCSPHHIKRSVVEAMQRQAR 1846

  Fly   174 -----DKI-------PSLNGFAKLKRRRSSCVGAPTPNSKRSKNNMGVIAKRPPKGEYVVERIEC 226
                 |||       ..:|...|.|:.:         ...|:.||.  :.:||.:..      :|
  Rat  1847 KMCNYDKILATKKNLDHVNKILKAKKLQ---------RQARTGNNF--VKRRPGRPR------KC 1894

  Fly   227 -----VEMDQYQPVFFV-------KWLGYHDSENTWESLANVADC--------AEMEKFVERHQQ 271
                 |.|..:|...||       :.:..|.|.:|   :.:|.:.        :|.:|..:|...
  Rat  1895 PLQAVVSMQAFQAAQFVNPELNEGEEVSLHLSPDT---VTDVIEAVVQSVNLNSEHKKGWKRKNW 1956

  Fly   272 LYEIYIAK----ITTE---------LEKQLEALPLMENITVAEVDAYEPLNLQIDLILLAQYRAA 323
            |.|....|    :..|         :||.:|....:|  |.||....|. |||..|.|:.:.:
  Rat  1957 LLEEQTRKKQKTVPEEEEQENNKSFIEKPVEIPSPLE--TPAEPSEPES-NLQPVLALIPREK-- 2016

  Fly   324 GSRSQREPQKIGERA-------------LKSMQIKR---------------------AQFVRRK- 353
              ::.|.|:|..:||             .:.:|:|:                     .:::|:|
  Rat  2017 --KAPRPPKKKYQRAGLYSDVYKTTDPKSRLIQLKKEKLEYTPGEHEYGLFPAPIHVGKYLRQKR 2079

  Fly   354 ---QLADLALFEKRMNHV-EKPSPPI--RVENNIDLDTIDSNFMYIHDNIIGKDVPKPEAGIVGC 412
               ||....|::.:.|.: :||..|:  ::.:|:.:|.              |.:...||....|
  Rat  2080 IDFQLPYDILWQWKHNQLYKKPDVPLYKKIRSNVYVDV--------------KPLSGYEATTCNC 2130

  Fly   413 KCTEDTEECTASTKCCARFAGELFAYERSTRRLRLRPGSAIYECN-SRCSCDSSCSNRLVQHGRQ 476
            |..:|.........|..|.   :||                 ||: :.|.|...|.|:.:|....
  Rat  2131 KKPDDDTRKGCGDDCLNRM---IFA-----------------ECSPNTCPCGEQCCNQRIQRHEW 2175

  Fly   477 VPLVLFKTANGSGWGVRAATALRKGEFVCEYIGEIITSDE-ANERGKAYDDNGRTYLFDLDYNTA 540
            |..:....|...|||:|....|:.|:|:.||:||:::..| .|...:.|.::...|..:|
  Rat  2176 VQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNL----- 2235

  Fly   541 QDSEYTIDAANYGNISHFINHSCDPNLAVFPCWIEHLNV-ALPHLVFFTLRPIKAGEELSFDYIR 604
             ||...||:...||.:.|||||||||     |.::..:| .:..:..:.|:.:.||.||::||
  Rat  2236 -DSGMVIDSYRMGNEARFINHSCDPN-----CEMQKWSVNGVYRIGLYALKDVPAGTELTYDY-- 2292

  Fly   605 ADNEDVPYENLSTAVRVECRCGADNCRKVL 634
                  .:.:.:...:..|:||.:.||.::
  Rat  2293 ------NFHSFNVEKQQLCKCGFEKCRGII 2316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-9	NP_524357.2	PTZ00327	11..>80	CDD:240362
		Chromo	219..268	CDD:459793	12/68 (18%)
		SET_SUV39H	388..634	CDD:380940	64/248 (26%)
Ash1l	XP_063137913.1	None