DRSC/TRiP Functional Genomics Resources

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Protein Alignment Su(var)3-9 and G9a

DIOPT Version :9

Sequence 1:NP_524357.2 Gene:Su(var)3-9 / 41483 FlyBaseID:FBgn0263755 Length:635 Species:Drosophila melanogaster
Sequence 2:NP_001259088.1 Gene:G9a / 30971 FlyBaseID:FBgn0040372 Length:1657 Species:Drosophila melanogaster


Alignment Length:357 Identity:105/357 - (29%)
Similarity:152/357 - (42%) Gaps:104/357 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   301 EVDAYEPLNLQIDLILLAQYRAAGSRSQREPQKIGERALKSMQIKRAQFVRRKQLADLALFEKRM 365
            ::.::.||.|:..::      .|.:.:.||.:.|             |.||.    :||:.|.. 
  Fly  1342 QMRSFRPLGLRTFVV------CADASNGREARPI-------------QVVRN----ELAMSENE- 1382

  Fly   366 NHVEKPSPPIRVENNIDLDTIDS----NFMY-----IHDNIIGKDVPKPEAGIVGC--KCTEDTE 419
                              |..||    :|.|     |..|.:..|....:..|..|  .|:.|..
  Fly  1383 ------------------DEADSLMWPDFRYVTQCIIQQNSVQIDRRVSQMRICSCLDSCSSDRC 1429

  Fly   420 EC---------TASTKCCARFAGELFAYERSTRRLRLRPGSAIYECNSRCSCDS-SCSNRLVQHG 474
            :|         ||.::..|.     |.||         ..:.|:|||..|.|:. ||.||:||:|
  Fly  1430 QCNGASSQNWYTAESRLNAD-----FNYE---------DPAVIFECNDVCGCNQLSCKNRVVQNG 1480

  Fly   475 RQVPLVLFKTAN-GSGWGVRAATALRKGEFVCEYIGEIITSDEANERGKAYDDNGRTYLFDLDYN 538
            .:.||.:.:..: ..||||||...:.||.||..|.|||:|:.||:.|   .||   :|.|||   
  Fly  1481 TRTPLQIVECEDQAKGWGVRALANVPKGTFVGSYTGEILTAMEADRR---TDD---SYYFDL--- 1536

  Fly   539 TAQDSEYTIDAANYGNISHFINHSCDPNLAVFPCWIEHLNVALPHLVFFTLRPIKAGEELSFDY- 602
               |:.:.|||..|||::.|.||||:||:.....:.||.:...|.:.||:.|.|.||||:.||| 
  Fly  1537 ---DNGHCIDANYYGNVTRFFNHSCEPNVLPVRVFYEHQDYRFPKIAFFSCRDIDAGEEICFDYG 1598

  Fly   603 ---IRADNEDVPYENLSTAVRVECRCGADNCR 631
               .|.::...          |.|||....|:
  Fly  1599 EKFWRVEHRSC----------VGCRCLTTTCK 1620

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Su(var)3-9NP_524357.2 P-loop_NTPase 41..>80 CDD:304359
CHROMO 217..268 CDD:237991
PreSET 362..455 CDD:128744 21/112 (19%)
SET 477..609 CDD:214614 55/136 (40%)
G9aNP_001259088.1 ATP-synt_B 150..248 CDD:304375
Ank_2 1056..1152 CDD:289560
ANK 1088..1217 CDD:238125
ANK repeat 1088..1120 CDD:293786
ANK repeat 1124..1153 CDD:293786
Ank_2 1127..1249 CDD:289560
ANK 1155..1306 CDD:238125
ANK repeat 1155..1196 CDD:293786
ANK repeat 1199..1249 CDD:293786
Ank_2 1205..1316 CDD:289560
ANK repeat 1251..1283 CDD:293786
ANK repeat 1285..1316 CDD:293786
PreSET 1357..1466 CDD:128744 33/158 (21%)
SET 1495..1602 CDD:214614 52/118 (44%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45467613
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1082
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D753093at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R211
SonicParanoid 00.000 Not matched by this tool.
54.780

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