DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Su(var)3-9 and set-8

DIOPT Version :9

Sequence 1:	NP_524357.2	Gene:	Su(var)3-9 / 41483	FlyBaseID:	FBgn0263755	Length:	635	Species:	Drosophila melanogaster
Sequence 2:	NP_001359546.1	Gene:	set-8 / 184086	WormBaseID:	WBGene00008527	Length:	407	Species:	Caenorhabditis elegans

Alignment Length:	159	Identity:	46/159 - (28%)
Similarity:	71/159 - (44%)	Gaps:	20/159 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   480 VLFKTANGSGWGVRAATALRKGEFVCEYIGEIITSDEANER---GKAYDDNG-RTYLFDLD---Y 537
            :|.|.....|:||.|...|..|..:.:|.||.|:..|...|   .|..:|.. :.|.|.:.   .
Worm   253 LLLKFEKNKGYGVFATKILENGCVIGQYCGEYISEKEKARRDALAKVCNDKECKFYSFQVKLELL 317

  Fly   538 NTAQDSEYTIDAANYGNISHFINHSCDPNLAVFPCWIEHLNVALPHLVFFTLRPIKAGEELSFDY 602
            |..|..:..:|.::..||:..:|.||:||.......|...|:.:.::|..|.|.||.||||:.:|
Worm   318 NELQAQKVYVDGSSVKNITAILNTSCEPNCTAIVEEISIQNIRIEYIVIKTKRTIKVGEELTINY 382

  Fly   603 IRADNEDVPYENLSTAVRVECRCGADNCR 631
                     ..|.|    .:|.||::.|:
Worm   383 ---------KWNSS----FKCFCGSEKCK 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-9	NP_524357.2	P-loop_NTPase	41..>80	CDD:304359
		CHROMO	217..268	CDD:237991
		PreSET	362..455	CDD:128744
		SET	477..609	CDD:214614	40/135 (30%)
set-8	NP_001359546.1	SET	<106..400	CDD:225491	46/159 (29%)
set-8	NP_001359546.1	SET	251..389	CDD:214614	42/148 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165858
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840