DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Su(var)3-9 and set-23

DIOPT Version :9

Sequence 1:	NP_524357.2	Gene:	Su(var)3-9 / 41483	FlyBaseID:	FBgn0263755	Length:	635	Species:	Drosophila melanogaster
Sequence 2:	NP_741320.1	Gene:	set-23 / 176969	WormBaseID:	WBGene00021515	Length:	244	Species:	Caenorhabditis elegans

Alignment Length:	256	Identity:	80/256 - (31%)
Similarity:	117/256 - (45%)	Gaps:	31/256 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   389 NFMYIHDNIIGKDVPKPEAGIV--GCKCTEDTEECTASTKC-CARFAGELFAYERSTRRLRLRPG 450
            |:..|...|.|..:.:.:...|  ||.|   ..||:::..| |.....:.:..:....    :..
Worm     2 NYEKIDSTIPGPGISETDWNDVFEGCNC---EAECSSAAGCSCLINKIDNYTVDGKIN----KSS 59

  Fly   451 SAIYECNSRCSC---DSSCSNRLVQHGRQVPLVLFKTAN-GSGWGVRAATALRKGEFVCEYIGEI 511
            ..:.||:.:|:|   .:||.||:||.|.|..|.:|.|.. ..|:||||...:..|||||||.||.
Worm    60 ELLIECSDQCACILLPTSCRNRVVQCGPQKKLEIFSTCEMAKGFGVRAGEQIAAGEFVCEYAGEC 124

  Fly   512 ITSDEANERGKAY--DDNGRTYLFDL-DYNTAQDSEYTIDAANYGNISHFINHSCDPNLAVFPCW 573
            |...|...|.:.:  |||   |...| ::...:..:..:|....|||..|:||||:||..:.
Worm   125 IGEQEVERRCREFRGDDN---YTLTLKEFFGGKPVKTFVDPRLRGNIGRFLNHSCEPNCEII--- 183

  Fly   574 IEHLNVALPHLVFFTLRPIKAGEELSFDYIRADNEDVPYENLSTAVRVECRCGADNCRKVL 634
            :..|...:|....|..|.|..||||.:||   .:..:..||     |..|.|.::.|||.|
Worm   184 LARLGRMIPAAGIFAKRDIVRGEELCYDY---GHSAIEGEN-----RKLCLCKSEKCRKYL 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-9	NP_524357.2	P-loop_NTPase	41..>80	CDD:304359
		CHROMO	217..268	CDD:237991
		PreSET	362..455	CDD:128744	12/68 (18%)
		SET	477..609	CDD:214614	47/135 (35%)
set-23	NP_741320.1	Pre-SET	<6..81	CDD:282838	17/81 (21%)
set-23	NP_741320.1	SET	89..213	CDD:214614	47/132 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D753093at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920