Protein Alignment Su(var)3-9 and set-2

DIOPT Version :10

• Sequence 1: NP_524357.2
• Gene: Su(var)3-9 / 41483
• FlyBaseID: FBgn0263755
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_498039.1
• Gene: set-2 / 175662
• WormBaseID: WBGene00004782
• Length: 1510
• Species: Caenorhabditis elegans
• Alignment Length: 855
• Identity: 178/855 - (20%)
• Similarity: 273/855 - (31%)
• Gaps: 326/855 - (38%)

  Fly    15 QKQDLSNLDVSKLTPL-------SPEVISRQATINI---------GTIGHVAHGKSTVVKAISGV 63
            ::|||..:.::: ||:       ..:.:||:...:|         ..:....|     :|||:..
 Worm   746 KRQDLERIAIAR-TPIVKKCKKRMMDELSRKVAEDIRQQIMRQCFAALDEKLH-----LKAIADE 804

  Fly    64 QTVRFKNELERNITIKLERLSEKKIKNLLTSK--QQRQQYEIKQRSMLR--------HLAELRRH 118
            :  :.|.|.|.....:.|:.|...|.:::.|:  ...|.:....|...|        |......|
 Worm   805 E--KRKKEREEKARQEAEKPSNHLIADMMPSQTLYNNQSFASSSRGFYRKQKPIPKSHPKHQEHH 867

  Fly   119 SRFRRLCTKPASSSMPASTSSVDRRTTRRSTSQTSLSPSNSSGYGSV---FGCEEHDVDKIP--- 177
            ...:      ||.|.|..:||..|.::...|.|.::|.|:||...:.   ...:|.|.|..|
 Worm   868 HHAK------ASVSTPVHSSSTSRNSSVAPTPQRTVSTSSSSSSAATSARVSEDESDSDSTPGEV 926

  Fly   178 ---SLNGFAKLKRRR-------------------------------SSCVGAPTPNSKRSKNNM- 207
               ..:..:..||||                               ||.....|.:.|..|..:
 Worm   927 QRRKTSVLSNDKRRRRASFSSTSIQSSPERQRDVSSSSRTSSSSSTSSMKQEETADEKSRKRKLI 991

  Fly   208 --------------GVIAKR--------------PPK----GEYVVERIECVEMDQ--------- 231
                          .|::.|              |||    .:::.||:..:|.::
 Worm   992 MSSDESSTTGSTATSVVSSRQSSLEPQQEKTDGEPPKKKSQTDFISERVSKIEGEERPLPEPVET 1056

  Fly   232 ---------YQPVFFVKW-----------------------------LGYHDSEN---------- 248
                     |.|...|.|                             .|..|...
 Worm  1057 SGPIIGDSSYLPYKIVHWEKAGIIEMNLPANSIRAHEYHPFTTEHCYFGIDDPRQPKIQIFDHSP 1121

  Fly   249 ---------------TWESLANVADCAEMEKFVERHQQLYEIYIAKITTELEKQLEALPLMENIT 298
                           .|..:.|||:...:            ||:..:|.....|.:..|..:
 Worm  1122 CKSEPGSEPLKITPAPWGPIDNVAETGPL------------IYMDVVTAPKTVQKKQKPRKQ--- 1171

  Fly   299 VAEVDAYE------------PLNLQIDLILLAQYRAAGSRSQREPQK-IGE-------------- 336
            |.|.|.||            |...:         :....||:.|.:| ||:
 Worm  1172 VFEKDPYEYYEPPPTKRPAPPPRFK---------KTFKPRSEEEKKKIIGDCEDLPDLEDQWYLR 1227

  Fly   337 RALKSMQ--IKRAQFVRRKQLADLALFEKRMNHVEKP---SPPIRVENNI-DLDTIDSNFMYIHD 395
            .||..||  :|.|..:..|::    |..|.|...|.|   ..|||.:..: |....|...    |
 Worm  1228 AALNEMQSEVKSADELPWKKM----LTFKEMLRSEDPLLRLNPIRSKKGLPDAFYEDEEL----D 1284

  Fly   396 NIIGKDVPKPEAGIVGCKCTEDTEECTASTKCCARFAGELFAYERSTRRLRLRPG-----SAIY- 454
            .:|      |.|  .||......|:.|...|                |.|..||.     :||:
 Worm  1285 GVI------PVA--AGCSRARPYEKMTMKQK----------------RSLVRRPDNESHPTAIFS 1325

  Fly   455 ---ECNSRCSCDSSCSNRLVQHGRQVPL-------------------VLFKTANGSGWGVRAATA 497
               |...|....:|...||:|......|                   :.|..:...|||:.|..:
 Worm  1326 ERDETAIRHQHLASKDMRLLQRRLLTSLGDANNDFFKINQLKFRKKMIKFARSRIHGWGLYAMES 1390

  Fly   498 LRKGEFVCEYIGEIITSDEANERGKAYDDN--GRTYLFDLDYNTAQDSEYTIDAANYGNISHFIN 560
            :...|.:.||||:.|.|..|.||.|||:..  |.:|||.:|.:      :.|||...||.:.|||
 Worm  1391 IAPDEMIVEYIGQTIRSLVAEEREKAYERRGIGSSYLFRIDLH------HVIDATKRGNFARFIN 1449

  Fly   561 HSCDPNLAVFPCWIEHLNV-ALPHLVFFTLRPIKAGEELSFDYIRADNEDVPYENLSTAVRVECR 624
            |||.||     |:.:.|.: ....:|.::...||.|||:::||.....:|          :::|.
 Worm  1450 HSCQPN-----CYAKVLTIEGEKRIVIYSRTIIKKGEEITYDYKFPIEDD----------KIDCL 1499

  Fly   625 CGADNCRKVL 634
            |||..||..|
 Worm  1500 CGAKTCRGYL 1509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-9	NP_524357.2	PTZ00327	11..>80	CDD:240362	15/80 (19%)
		Chromo	219..268	CDD:459793	13/120 (11%)
		SET_SUV39H	388..634	CDD:380940	75/276 (27%)
set-2	NP_498039.1	RRM_SF	124..213	CDD:473069
		SET_SETD1	1359..1506	CDD:380946	51/167 (31%)