DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Su(var)3-9 and set-13

DIOPT Version :9

Sequence 1:	NP_524357.2	Gene:	Su(var)3-9 / 41483	FlyBaseID:	FBgn0263755	Length:	635	Species:	Drosophila melanogaster
Sequence 2:	NP_494371.1	Gene:	set-13 / 173626	WormBaseID:	WBGene00019690	Length:	402	Species:	Caenorhabditis elegans

Alignment Length:	350	Identity:	85/350 - (24%)
Similarity:	135/350 - (38%)	Gaps:	68/350 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   333 KIGERALKSMQIKRAQFVRRKQLADLALFEKRMNHVEKPSPPIRVENNI-DLDTID-------SN 389
            |:..|.|:|.....|...:.:...:    |..:..|.| .|.||:.:|: |....|       |.
Worm    31 KMSSRTLRSSSSSNAISTKTQPKTE----EAPLIPVTK-GPVIRMTSNMADKAQNDHSMWPSTSK 90

  Fly   390 FMYIHDNIIGKDVPKPEAGIV------------GCKCTEDTEECTASTKC-CARFAGELFAYERS 441
            |..|..|::|:.|.|.....:            ||:..:|   |:.:..| |.:.|..|..:..|
Worm    91 FESIWGNVLGERVNKSTIAAIREGMKIENKVTCGCRPGQD---CSTNPACRCFQTASRLREHFGS 152

  Fly   442 TRRLRLRPGSAI---------YECNSRCSCDSSCSNRLVQHGRQVPLVLFK--TANGSGWGVRAA 495
            ....|.:|...:         :.|:..|.|...|:...:|...:.|...||  ..:|.|:.|.:|
Worm   153 DILTRGKPVKTVDTMYWDRPMFACSGSCGCKGQCNLNALQDICEDPAKKFKITRTDGKGFCVYSA 217

  Fly   496 TALRKGEFVCEYIGEI-----ITSDEANERGKAYDDNGRTYLFDL---------DYN----TAQD 542
            ..::||..|.|:.|||     |.|:...|:......|..|.|.|.         .|.    :|..
Worm   218 RVIKKGSPVLEFSGEITDYLAIKSNADIEQYSIMLYNNETKLCDFFSKEENLSSKYKKILWSAYR 282

  Fly   543 SEYTIDAANYGNISHFINHSCDPNLAVFPCWIEHLNVALPHLVFFTLRPIKAGEELSFDYIRADN 607
            |:..|:..|.||.:.|.:|.|..|:.:...:....:.|...:|.|....||.|.||:|:|
Worm   283 SKAWINPLNRGNCARFFSHGCKANMELGRVFQGGFSPADMKIVLFAKEIIKPGTELTFNY----- 342

  Fly   608 EDVPYENLSTAVRVECRCGADNCRK 632
             ...|:.:....:  |.|.|  |:|
Worm   343 -GPSYKEIFLGNK--CLCEA--CKK 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-9	NP_524357.2	P-loop_NTPase	41..>80	CDD:304359
		CHROMO	217..268	CDD:237991
		PreSET	362..455	CDD:128744	27/122 (22%)
		SET	477..609	CDD:214614	42/151 (28%)
set-13	NP_494371.1	SET	200..348	CDD:214614	42/153 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165859
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740