DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4860 and Acox1

DIOPT Version :9

Sequence 1:	NP_650163.2	Gene:	CG4860 / 41480	FlyBaseID:	FBgn0037999	Length:	415	Species:	Drosophila melanogaster
Sequence 2:	NP_059036.1	Gene:	Acox1 / 50681	RGDID:	619757	Length:	661	Species:	Rattus norvegicus

Alignment Length:	431	Identity:	94/431 - (21%)
Similarity:	165/431 - (38%)	Gaps:	96/431 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 REFANAEL-APKARHHDREELYPAEQVRRLGELGLMSVTVREEYGGSGLD-----YQAYAIGMEE 107
            ||..|..| .|..:|.|...|..:::.....:.....|....|||.|..:     .:.|.....|
  Rat    34 REIENLILNDPDFQHEDYNFLTRSQRYEVAVKKSATMVKKMREYGISDPEEIMWFKKLYLANFVE 98

  Fly   108 VARGDAAVSIVMGVN-NLYLGAVQQHGTEQQKQDFLVPYTQGEHIAFYALSEPGNGSDAGAASTT 171
                      .:|:| ::::..:...||..|::.::.|..:.:.|..||.:|.|:|:......||
  Rat    99 ----------PVGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETT 153

  Fly   172 A----KLQG---DSYQINGTKAWISN-SKEASGGIVFATVDKSMKHKGITAFLTP-------KDV 221
            |    |.|.   :|..:...|.|... .|.::..||.|.:....:..|:.||:.|       |.:
  Rat   154 ATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPL 218

  Fly   222 PGLSIAKKESKMGMRATSTCQLVLEDVHVPRSRVL----GAAGDG--FKIAMQSLDCGR------ 274
            ||:::.....|.|........|.:::..:||..:|    ....||  .|.....|..|.
  Rat   219 PGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRS 283

  Fly   275 --IGIAAQATGIAQAALELAVDYSQKRVAFGKHLARLQLIQQ-----KLADMAT-RVEISRLLTW 331
              :|.|||:   ...|..:|:.||..|        |...|:|     ::.|..| :.::..||..
  Rat   284 FLVGNAAQS---LSKACTIAIRYSAVR--------RQSEIKQSEPEPQILDFQTQQYKLFPLLAT 337

  Fly   332 RAA------WLKDNGLPITKE------AAMAKLHASES-----ATFCAH----QCIQILGGMGY- 374
            ..|      ::|:..|.|.:.      :.:.:|||..:     .|:.|:    :|....||.||
  Rat   338 AYAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYS 402

  Fly   375 -TTDLPAELYYRNARVTE----IYEGTSEIQRIVIANAVLR 410
             ::.:|      |..||.    .:||.:.:..:..|..:::
  Rat   403 HSSGIP------NIYVTFTPACTFEGENTVMMLQTARFLMK 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4860	NP_650163.2	CaiA	37..414	CDD:224871	94/431 (22%)
CG4860	NP_650163.2	SCAD_SBCAD	39..410	CDD:173847	94/429 (22%)
Acox1	NP_059036.1	AXO	3..638	CDD:173839	94/431 (22%)
Acox1	NP_059036.1	Microbody targeting signal	659..661
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810