DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4860 and acads

DIOPT Version :9

Sequence 1:	NP_650163.2	Gene:	CG4860 / 41480	FlyBaseID:	FBgn0037999	Length:	415	Species:	Drosophila melanogaster
Sequence 2:	NP_001003743.1	Gene:	acads / 445288	ZFINID:	ZDB-GENE-040808-64	Length:	405	Species:	Danio rerio

Alignment Length:	394	Identity:	228/394 - (57%)
Similarity:	303/394 - (76%)	Gaps:	4/394 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 RIIAGGNRGIAC---LAALSETHQILQKTCREFANAELAPKARHHDREELYPAEQVRRLGELGLM 83
            |::....||:.|   ||.|.|.||::::|||::|..||||.|...|:|..:||:||:.||.:|:|
Zfish     9 RVVMALGRGVRCLTQLAELPELHQMMRQTCRDYAQKELAPIAGLLDKEHRFPAKQVQELGAMGVM 73

  Fly    84 SVTVREEYGGSGLDYQAYAIGMEEVARGDAAVSIVMGVNN-LYLGAVQQHGTEQQKQDFLVPYTQ 147
            :|.|.|..||:|:||.||.:.:||::||.|:..:::.||| ||:|.:.:.|:|:||:.::.|:|.
Zfish    74 AVEVPESLGGAGMDYLAYCLAVEELSRGCASTGVIVSVNNSLYIGPILKFGSEEQKKQWITPFTT 138

  Fly   148 GEHIAFYALSEPGNGSDAGAASTTAKLQGDSYQINGTKAWISNSKEASGGIVFATVDKSMKHKGI 212
            ||.:..:||||||||||||||||.|:.:|:.:.:|||||||:||.:||..:||||.|||:|||||
Zfish   139 GEKVGCFALSEPGNGSDAGAASTLAQQEGNEWVLNGTKAWITNSWDASATVVFATTDKSLKHKGI 203

  Fly   213 TAFLTPKDVPGLSIAKKESKMGMRATSTCQLVLEDVHVPRSRVLGAAGDGFKIAMQSLDCGRIGI 277
            :|||.|...||||:.|||.|:|:||:||..::|||..:|...:||..|.|||||||:||.||:||
Zfish   204 SAFLVPMPHPGLSLGKKEDKLGIRASSTANIILEDCRIPLGNMLGERGMGFKIAMQTLDSGRLGI 268

  Fly   278 AAQATGIAQAALELAVDYSQKRVAFGKHLARLQLIQQKLADMATRVEISRLLTWRAAWLKDNGLP 342
            ||||.|||||||:.|.||:.||.|||..:.:||.||.||||||..:|.:|||||:||.|:|...|
Zfish   269 AAQALGIAQAALDCAADYAHKRTAFGAPIGKLQAIQFKLADMAVAIESARLLTWKAALLRDAKKP 333

  Fly   343 ITKEAAMAKLHASESATFCAHQCIQILGGMGYTTDLPAELYYRNARVTEIYEGTSEIQRIVIANA 407
            .|||||||||.|||:|||.:||.||:||||||.||:|||.:||:||:||||||||||||:||||.
Zfish   334 FTKEAAMAKLAASEAATFASHQAIQVLGGMGYVTDMPAERHYRDARITEIYEGTSEIQRLVIANN 398

  Fly   408 VLRE 411
            :|:|
Zfish   399 ILKE 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4860	NP_650163.2	CaiA	37..414	CDD:224871	222/376 (59%)
CG4860	NP_650163.2	SCAD_SBCAD	39..410	CDD:173847	219/371 (59%)
acads	NP_001003743.1	CaiA	26..405	CDD:224871	222/377 (59%)
acads	NP_001003743.1	SCAD_SBCAD	29..401	CDD:173847	219/371 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61069
OrthoDB	1	1.010	-	-		D350722at33208
OrthoFinder	1	1.000	-	-		FOG0000508
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43884
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5348
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.930