DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4860 and CG3902

DIOPT Version :9

Sequence 1:	NP_650163.2	Gene:	CG4860 / 41480	FlyBaseID:	FBgn0037999	Length:	415	Species:	Drosophila melanogaster
Sequence 2:	NP_649069.2	Gene:	CG3902 / 40059	FlyBaseID:	FBgn0036824	Length:	414	Species:	Drosophila melanogaster

Alignment Length:	379	Identity:	142/379 - (37%)
Similarity:	226/379 - (59%)	Gaps:	2/379 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 LAALSETHQILQKTCREFANAELAPKARHHDREELYPAEQVRRLGELGLMSVTVREEYGGSGLDY 98
            |..|::..:::::|..:.|..::.|..:..|.|..:....|:.:.|.|||.:.:..|.||||.::
  Fly    34 LTFLTDDEKMMKETVAKLAQEQIQPLVKKMDFEHKFDPSVVKAVFENGLMGIEIDTELGGSGCNF 98

  Fly    99 QAYAIGMEEVARGDAAVSIVMGVNNLYLGAVQ-QHGTEQQKQDFLVPYTQGEHIAFYALSEPGNG 162
            ....:.:||:::.|.||:..:.::|..:.::. :.|..:||..:| |....|:...:||:|||.|
  Fly    99 MTNIVVVEELSKIDPAVAAFVDIHNTLVNSLMIKFGNAEQKAKYL-PKLAQEYAGSFALTEPGAG 162

  Fly   163 SDAGAASTTAKLQGDSYQINGTKAWISNSKEASGGIVFATVDKSMKHKGITAFLTPKDVPGLSIA 227
            |||.:..|.||..|..|.|||:|.|||||..|...::||.......::|||.|:..::.|||.:.
  Fly   163 SDAFSLKTVAKKDGSHYVINGSKMWISNSDVAGVFLIFANAKPEDGYRGITTFIVDRETPGLIVN 227

  Fly   228 KKESKMGMRATSTCQLVLEDVHVPRSRVLGAAGDGFKIAMQSLDCGRIGIAAQATGIAQAALELA 292
            |.|.|:|:||:.||||..::|.||...:||..|.|:|.|...|:.||||||||..|:||...:..
  Fly   228 KPEDKLGIRASGTCQLTFDNVRVPEENILGTFGHGYKYAAGFLNEGRIGIAAQMVGLAQGTFDAT 292

  Fly   293 VDYSQKRVAFGKHLARLQLIQQKLADMATRVEISRLLTWRAAWLKDNGLPITKEAAMAKLHASES 357
            :.|..:|..||..:...|.:|.::|.:||.:|.:||:|:.||.|::.|:|..|||||||.:|||.
  Fly   293 IPYLLERKQFGDAIYNFQSMQHQIATVATEIEAARLMTYNAARLQEQGVPFQKEAAMAKYYASEV 357

  Fly   358 ATFCAHQCIQILGGMGYTTDLPAELYYRNARVTEIYEGTSEIQRIVIANAVLRE 411
            |...|.:|:..:||:|:|.|.|.|.|||:.::..|||||:.:|...||..:.::
  Fly   358 AQRAAIKCVDWMGGVGFTRDFPQEKYYRDVKIGAIYEGTTNMQLSTIAKCIKKD 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4860	NP_650163.2	CaiA	37..414	CDD:224871	141/376 (38%)
CG4860	NP_650163.2	SCAD_SBCAD	39..410	CDD:173847	140/371 (38%)
CG3902	NP_649069.2	CaiA	37..414	CDD:224871	141/376 (38%)
CG3902	NP_649069.2	SCAD_SBCAD	39..410	CDD:173847	140/371 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460756
Domainoid	1	1.000	97	1.000	Domainoid score	I372
eggNOG	1	0.900	-	-		E1_COG1960
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	183	1.000	Inparanoid score	I179
Isobase	1	0.950	-	0	Normalized mean entropy	S1951
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D589058at2759
OrthoFinder	1	1.000	-	-		FOG0000508
OrthoInspector	1	1.000	-	-		mtm9754
orthoMCL	1	0.900	-	-		OOG6_102170
Panther	1	1.100	-	-	P	PTHR43884
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	11	10.750