DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4860 and CG6638

DIOPT Version :9

Sequence 1:	NP_650163.2	Gene:	CG4860 / 41480	FlyBaseID:	FBgn0037999	Length:	415	Species:	Drosophila melanogaster
Sequence 2:	NP_648239.1	Gene:	CG6638 / 38979	FlyBaseID:	FBgn0035911	Length:	420	Species:	Drosophila melanogaster

Alignment Length:	387	Identity:	144/387 - (37%)
Similarity:	213/387 - (55%)	Gaps:	15/387 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 LSETHQILQKTCREFANAELAPKARHHDR----EELYPAEQVRRLGELGLMSVTVREEYGGSGLD 97
            |.|..|.|::....|...||||.|:..|:    :::.|.  .::||.||.:.:|...::||:|..
  Fly    39 LDEDRQKLREVAFNFFQKELAPLAKEIDKLDNFKDMRPF--WKKLGALGFLGITAEPDFGGTGGS 101

  Fly    98 YQAYAIGMEEVARGDAAVSIVMGV-NNLYLGAVQQHGTEQQKQDFLVPYTQGEHIAFYALSEPGN 161
            |..:.|.|||.:|....|::..|. :||.:..:.::||.:||:.:|.....|||:...|:||||.
  Fly   102 YLDHCIIMEEFSRAAGGVALSYGAHSNLCINQLTKNGTPEQKEKYLPKLCSGEHVGGLAMSEPGA 166

  Fly   162 GSDAGAASTTAKLQGDSYQINGTKAWISNSKEASGGIVFATVDKS---MKHKGITAFLTPKDVPG 223
            |||..:....|:.:||.|.:||:|.||:|..:|...||:|....|   .|| |||||:......|
  Fly   167 GSDVVSMKLRAERKGDYYVLNGSKFWITNGSDADTLIVYAKTGGSGVPDKH-GITAFIVETAWEG 230

  Fly   224 LSIAKKESKMGMRATSTCQLVLEDVHVPRSRVLGAAGDGFKIAMQSLDCGRIGIAAQATGIAQAA 288
            .|:|:|..|:|||.:|||:||.:|:.||...:||....|..:.|..||..|:.:||...|:.|||
  Fly   231 FSVAQKLDKLGMRGSSTCELVFQDLKVPAKNILGQENRGVYVLMSGLDFERLVLAAGPVGLMQAA 295

  Fly   289 LELAVDYSQKRVAFGKHLARLQLIQQKLADMATRVEISRLLTWRAAWLKDNGLPITKEAAMAKLH 353
            .::|.||:.:|....|.:...||:|.|:|||.|.:...|...:..|...|.|....|:.|...|:
  Fly   296 CDVAFDYAHQRKQMNKLIGEFQLLQGKMADMYTTLSACRSYLYTVARSCDAGNRSPKDCAGVILY 360

  Fly   354 ASESATFCAHQCIQILGGMGYTTDLPAELYYRNARVTEIYEGTSEIQRIVIANAVLRELGKE 415
            .:|.||..|...||||||.||..:.|.....|:|::.||..|||||:|.:|.    |:|.:|
  Fly   361 TAEKATKVALDAIQILGGNGYINENPTGRILRDAKLYEIGAGTSEIRRWLIG----RQLNQE 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4860	NP_650163.2	CaiA	37..414	CDD:224871	143/384 (37%)
CG4860	NP_650163.2	SCAD_SBCAD	39..410	CDD:173847	140/378 (37%)
CG6638	NP_648239.1	PLN02519	14..418	CDD:215284	143/385 (37%)
CG6638	NP_648239.1	IVD	38..417	CDD:173845	143/384 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460746
Domainoid	1	1.000	70	1.000	Domainoid score	I509
eggNOG	1	0.900	-	-		E1_COG1960
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	183	1.000	Inparanoid score	I179
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D589058at2759
OrthoFinder	1	1.000	-	-		FOG0000508
OrthoInspector	1	1.000	-	-		mtm9754
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43884
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.900