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Protein Alignment CG4860 and GCDH

DIOPT Version :9

Sequence 1:	NP_650163.2	Gene:	CG4860 / 41480	FlyBaseID:	FBgn0037999	Length:	415	Species:	Drosophila melanogaster
Sequence 2:	NP_000150.1	Gene:	GCDH / 2639	HGNCID:	4189	Length:	438	Species:	Homo sapiens

Alignment Length:	370	Identity:	113/370 - (30%)
Similarity:	185/370 - (50%)	Gaps:	11/370 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 ILQKTCREFANAELAPKARHHDREELYPAEQVRRLGELGLMSVTVREEYGGSGLDYQAYAIGMEE 107
            :::.|.|.:....|.|:....:|.|::..|.:..:||||::..|:: .||.:|:...||.:...|
Human    66 LIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIK-GYGCAGVSSVAYGLLARE 129

  Fly   108 VARGDAAVSIVMGV-NNLYLGAVQQHGTEQQKQDFLVPYTQGEHIAFYALSEPGNGSDAGAASTT 171
            :.|.|:.....|.| ::|.:..:..:|:|:|:|.:|....:||.:..:.|:||.:|||..:..|.
Human   130 LERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETR 194

  Fly   172 AKLQGD--SYQINGTKAWISNSKEASGGIVFATVDKSMKHKGITAFLTPKDVPGLSIAKKESKMG 234
            |.....  ||.:||||.||:||..|...:|:|..:...    |..||..|.:.|||..:.:.|..
Human   195 AHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGC----IRGFLLEKGMRGLSAPRIQGKFS 255

  Fly   235 MRATSTCQLVLEDVHVPRSRVL-GAAGDGFKIAMQSLDCGRIGIAAQATGIAQAALELAVDYSQK 298
            :||::|..::::.|.||...|| ||:..|....  .|:..|.|||....|.::..|..|..|:..
Human   256 LRASATGMIIMDGVEVPEENVLPGASSLGGPFG--CLNNARYGIAWGVLGASEFCLHTARQYALD 318

  Fly   299 RVAFGKHLARLQLIQQKLADMATRVEISRLLTWRAAWLKDNGLPITKEAAMAKLHASESATFCAH 363
            |:.||..|||.||||:|||||.|.:.:......:...|||......:..::.|.:....|...|.
Human   319 RMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIAR 383

  Fly   364 QCIQILGGMGYTTDLPAELYYRNARVTEIYEGTSEIQRIVIANAV 408
            |...:|||.|.:.:.....:..|......||||.:|..:::..|:
Human   384 QARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAI 428

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.