DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4830 and 4CL5

DIOPT Version :9

Sequence 1:	NP_650160.1	Gene:	CG4830 / 41477	FlyBaseID:	FBgn0037996	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	NP_188760.3	Gene:	4CL5 / 821677	AraportID:	AT3G21230	Length:	570	Species:	Arabidopsis thaliana

Alignment Length:	507	Identity:	142/507 - (28%)
Similarity:	235/507 - (46%)	Gaps:	37/507 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 CQISDSEGVEVTFGQALTWAIRIAQQLKSRGLDHKDIIGISARNTTYIMPTAVACFFHGTPFQSA 110
            |.|..:.|..:|:....|...|||..:...|:.|.|::.:...|:.....:.:|..:.|....:|
plant    64 CIIDGATGRILTYADVQTNMRRIAAGIHRLGIRHGDVVMLLLPNSPEFALSFLAVAYLGAVSTTA 128

  Fly   111 NPILEESTLKHLYNISKPKIIFTDADHYDKLYSATSAFKPEIIL-----------TTGTKDGVLS 164
            ||...:..:......|..|:|.|.....|||   |:.....:::           .:.:.||.:|
plant   129 NPFYTQPEIAKQAKASAAKMIITKKCLVDKL---TNLKNDGVLIVCLDDDGDNGVVSSSDDGCVS 190

  Fly   165 IQDLLAPTKTEFFYQPTPLKEGPSQTVAILTSSGTTGMPKAVCISN-DILTQETVFVNG------ 222
            ..:|....:||.. :|   |..|..|||:..||||||:||.|.|:: .::|.....|:|
plant   191 FTELTQADETELL-KP---KISPEDTVAMPYSSGTTGLPKGVMITHKGLVTSIAQKVDGENPNLN 251

  Fly   223 ---YDTIFISASLDWITGLWATIFSTVNGCTRIISSKPFAADYFVYLVSKYSITYALIPPEHCCS 284
               .|.|.....:..|..|.|.:.|.:.....::....|..:..:.|:.:|.:|...:.|....:
plant   252 FTANDVILCFLPMFHIYALDALMLSAMRTGAALLIVPRFELNLVMELIQRYKVTVVPVAPPVVLA 316

  Fly   285 LLDCPTATPEKLGSLTKLNFGGGRMTQATVERVKKLAPNGVLNSSYGMTEVGFI------VFNHG 343
            .:..|......|.|:..:..|...:.:...:.|:...||.:....|||||.|.:      ..|..
plant   317 FIKSPETERYDLSSVRIMLSGAATLKKELEDAVRLKFPNAIFGQGYGMTESGTVAKSLAFAKNPF 381

  Fly   344 HLKLTAAGNPLPGIQVKIVD-DDGNQLGVNQTGEIIVHNGFSWNGYFADPEATKAMQDEEGWFHT 407
            ..|..|.|..:...::|:|| :.|..|..|::|||.|.......||..|||||....|::||.||
plant   382 KTKSGACGTVIRNAEMKVVDTETGISLPRNKSGEICVRGHQLMKGYLNDPEATARTIDKDGWLHT 446

  Fly   408 GDMGYFDEDDYLYMTDRKKEVLKWKGLQMWPAEVEAVIDELPEVKRVCVIGVYDETQGDVPGALV 472
            ||:|:.|:||.:::.||.||::|:||.|:.|||:||::...|.:....|:.:.||...:||.|.|
plant   447 GDIGFVDDDDEIFIVDRLKELIKFKGYQVAPAELEALLISHPSIDDAAVVAMKDEVADEVPVAFV 511

  Fly   473 VREDNATLTAQQVIDHVAKRLPDIQKQLRAGVQFADEIPQNHNGKVVRRYAR 524
            .|...:.||...|..:|.|::.. .|:::. |.|.:.||:..:||::|:..|
plant   512 ARSQGSQLTEDDVKSYVNKQVVH-YKRIKM-VFFIEVIPKAVSGKILRKDLR 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4830	NP_650160.1	CaiC	18..529	CDD:223395	142/507 (28%)
CG4830	NP_650160.1	AFD_class_I	46..518	CDD:302604	139/499 (28%)
4CL5	NP_188760.3	PLN02246	20..567	CDD:215137	142/507 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920