Protein Alignment CG4830 and ACSF2

DIOPT Version :9

• Sequence 1: NP_650160.1
• Gene: CG4830 / 41477
• FlyBaseID: FBgn0037996
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: NP_001275897.1
• Gene: ACSF2 / 80221
• HGNCID: 26101
• Length: 640
• Species: Homo sapiens
• Alignment Length: 568
• Identity: 115/568 - (20%)
• Similarity: 218/568 - (38%)
• Gaps: 104/568 - (18%)

  Fly    29 SLGRIIFKNMRNWPKNVCQISDSEGVEVTFGQALTWAIRIAQQLKSRGLDHKDIIGISARNTTYI 93
            ::|:.:....:..|:....:...|.|.:||.|......:.|..|.|.||...|.:|:...|:...
Human    98 TVGQCLETTAQRVPEREALVVLHEDVRLTFAQLKEEVDKAASGLLSIGLCKGDRLGMWGPNSYAW 162

  Fly    94 MPTAVACFFHGTPFQSANPILEESTLKH-LYNISKPKIIFTDADHYDKLYSATSAFKPEI----- 152
            :...:|....|....|.||..:...|:: |..:....::|.......:.|:......||:
Human   163 VLMQLATAQAGIILVSVNPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQP 227

  Fly   153 ---------ILTT-----GTKDGVLSIQDLLAPTKT-----------EFFYQPTPLKEGPSQTVA 192
                     .|||     ....|.|.:.:::|...|           :|.....|:.
Human   228 GALKSQRLPDLTTVISVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPIN-------- 284

  Fly   193 ILTSSGTTGMPKAVCIS-------NDIL---------TQETVFVNGYDTIFISASLDWITGLWAT 241
            |..:|||||.||...:|       ::||         |.|.:.:     |..:.....:..:..|
Human   285 IQFTSGTTGSPKGATLSHYNIVNNSNILGERLKLHEKTPEQLRM-----ILPNPLYHCLGSVAGT 344

  Fly   242 IFSTVNGCTRIISSKPFAADYFVYLVSKYSITYALIPPEHCCSLLDCPTATPEKLGSLTKLNFGG 306
            :...:.|.|.|::|..|.....:..:|:...|:....|.....:|:.|..:...:.::.     |
Human   345 MMCLMYGATLILASPIFNGKKALEAISRERGTFLYGTPTMFVDILNQPDFSSYDISTMC-----G 404

  Fly   307 G---------RMTQATVERV--KKLAPNGVLNSSYGMTEVGFIVFNH-----GHLKLTAAGNPLP 355
            |         .:.:|.:.::  |.|.      .:||.||...:.|.|     ...|..:.|..:|
Human   405 GVIAGSPAPPELIRAIINKINMKDLV------VAYGTTENSPVTFAHFPEDTVEQKAESVGRIMP 463

  Fly   356 GIQVKIVDDDGNQLG-VNQTGEIIVHNGFSWNGYFADPEATKAMQDEEGWFHTGDMGYFDEDDYL 419
            ..:.:|::.:...|. :|..||:.:.......||:.:|:.|:...|::.|:.|||:...:|..:.
Human   464 HTEARIMNMEAGTLAKLNTPGELCIRGYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQGFC 528

  Fly   420 YMTDRKKEVLKWKGLQMWPAEVEAVIDELPEVKRVCVIGVYDETQGDVPGALVVREDNATLTAQQ 484
            .:..|.|:::...|..::|||:|......|:|:.|.|:||.|:..|:...|.:..:|....|.::
Human   529 KIVGRSKDMIIRGGENIYPAELEDFFHTHPKVQEVQVVGVKDDRMGEEICACIRLKDGEETTVEE 593

  Fly   485 V-------IDHVAKRLPDIQKQLRAGVQFADEIPQNHNGKVVRRYARD 525
            :       |.|.  ::|..       :.|....|...:||:.:...|:
Human   594 IKAFCKGKISHF--KIPKY-------IVFVTNYPLTISGKIQKFKLRE 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4830	NP_650160.1	CaiC	18..529	CDD:223395	115/568 (20%)
		AFD_class_I	46..518	CDD:302604	111/542 (20%)
ACSF2	NP_001275897.1	PRK08315	82..640	CDD:236236	115/568 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810