DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4830 and acsf3

DIOPT Version :9

Sequence 1:	NP_650160.1	Gene:	CG4830 / 41477	FlyBaseID:	FBgn0037996	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	XP_021329817.1	Gene:	acsf3 / 562292	ZFINID:	ZDB-GENE-121026-3	Length:	579	Species:	Danio rerio

Alignment Length:	548	Identity:	118/548 - (21%)
Similarity:	204/548 - (37%)	Gaps:	120/548 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 IFKNMRNWPKNV-----CQISDSEGVEVTFGQALTWAIRIAQQLKSRGLDHKDIIGISARNTTYI 93
            ::||.:....::     ||..|.:|..::|                          :.|.:.:|.
Zfish    80 LYKNSKILAGHITKALTCQSGDLQGKRISF--------------------------LCANDASYT 118

  Fly    94 MP--TAVACFFHGTPFQSANPILEESTLKHLYNISKPKIIFTDADHYDKLYSATSAFKPEIILTT 156
            :.  .:..|.....|....:|:   |.|:::.:.|:..::.......|.|......
Zfish   119 VAQWASWMCGGIAVPLYRKHPL---SELEYVISDSQSSLLVAGQSFVDTLEPLAQK--------- 171

  Fly   157 GTKDGVLSIQDLLAPTKTEFFYQPTPLKEG-----PSQTVAILTSSGTTGMPKAVCISNDILTQE 216
                  |.:..|..|..:..|.....|.|.     ..:...::.:|||||.||.|..::..|
Zfish   172 ------LGLPCLKLPATSSQFEDTQTLPEDMISDWAERPAMLIYTSGTTGRPKGVLHTHSSL--- 227

  Fly   217 TVFVNGY---------DTIFISASLDWITG--------LW--ATI-----FSTVNGCTRIISSKP 257
            ...|.|.         |.|..:..|..:.|        ||  ||.     ||......::|.||.
Zfish   228 QAMVQGLVSEWAWHKDDVILHTLPLHHVHGIVNKLMCPLWVGATCIMLPDFSAQKVWEQLICSKS 292

  Fly   258 FAADYFVYLVSKYS--ITYALIPPEHCC--SLLDCPTAT-PEKLGSLTKLNFGGGRMTQATVERV 317
            ...:.|:.:.:.||  |.|.   .:|..  .:.|...|. .|::..:..   |...:.|..:||.
Zfish   293 PMVNVFMAVPTIYSKLIEYY---DQHFTQPQVQDFIRAVCKERIRLMVS---GSAALPQPVLERW 351

  Fly   318 KKLAPNGVLNSSYGMTEVGFIVFN--HGHLKLTAAGNPLPGIQVK------IVDDDGNQLGV--- 371
            .::..: ||...|||||:|..:.|  .|.....|.|.||||::|:      ||..:|...|.
Zfish   352 AEITDH-VLLERYGMTEIGMALSNSYKGPRVPGAVGVPLPGVEVRIMMNSSIVIAEGTSKGTQVK 415

  Fly   372 ----NQTGEIIVHNGFSWNGYFADPEATKAMQDEEGWFHTGDMGYFDEDDYLYMTDRKKEVLKWK 432
                .:.||::|.....:..|:..|:.|:....|:.||.|||...:.:..|..|.....:::|..
Zfish   416 AGLEGKEGELLVRGSSVFQKYWNKPQETEESFTEDRWFKTGDTALYRDGVYWIMGRTSVDIIKSG 480

  Fly   433 GLQMWPAEVEAVIDELPEVKRVCVIGVYDETQGDVPGALVVREDNATLTAQQV----IDHVAKRL 493
            |.::...:||..:...|::..|.|||..|.|.|....|:|......|:....:    .:|:|
Zfish   481 GYKISALDVERHLLAHPDITDVAVIGAPDATWGQKVTAVVQMRKGKTMILSDLKAWAREHMA--- 542

  Fly   494 PDIQKQLRAGVQFADEIPQNHNGKVVRR 521
               ...:..|:...:::|:|..|||.::
Zfish   543 ---SYSIPTGLILVEDMPRNQMGKVNKK 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4830	NP_650160.1	CaiC	18..529	CDD:223395	118/548 (22%)
CG4830	NP_650160.1	AFD_class_I	46..518	CDD:302604	114/526 (22%)
acsf3	XP_021329817.1	MCS	64..566	CDD:213307	118/545 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900