Protein Alignment CG4830 and SLC27A1

DIOPT Version :9

• Sequence 1: NP_650160.1
• Gene: CG4830 / 41477
• FlyBaseID: FBgn0037996
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: XP_011526302.1
• Gene: SLC27A1 / 376497
• HGNCID: 10995
• Length: 658
• Species: Homo sapiens
• Alignment Length: 591
• Identity: 129/591 - (21%)
• Similarity: 203/591 - (34%)
• Gaps: 157/591 - (26%)

  Fly    29 SLGRIIFKNMRNWPKNVCQISDSEGVEVTFGQALTWAIRIAQQLKSRGLDHKDIIGISARNTTYI 93
            ::.||....::..|:.:..:....|...||.|...::..:|...:..|....|:
Human    77 TIPRIFQAVVQRQPERLALVDAGTGECWTFAQLDAYSNAVANLFRQLGFAPGDV----------- 130

  Fly    94 MPTAVACFFHGTP-------------FQSA--NPILEESTLKHLYNISKPKIIFTDADHYDKLYS 143
                ||.|..|.|             .::|  |..|....|......|..|.:....:....:..
Human   131 ----VAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALIFGGEMVAAVAE 191

  Fly   144 ATSAFKPEII-LTTGT--KDGVLSIQDLLAPTKTEFFYQPTPLKEGPSQ----TVAILTSSGTTG 201
            .:......:| ..:|.  .:|:|....||.|...|  ....||.:.||:    .:..:.:|||||
Human   192 VSGHLGKSLIKFCSGDLGPEGILPDTHLLDPLLKE--ASTAPLAQIPSKGMDDRLFYIYTSGTTG 254

  Fly   202 MPKAVCISNDILTQETVFVNG----------YDTIFISASLDWITGLWATIFSTVNGCTRIISSK 256
            :|||..:.:....:...|.:.          ||.:.:..|...|.|:...:   :.|.| ::..|
Human   255 LPKAAIVVHSRYYRMAAFGHHAYRMQAADVLYDCLPLYHSAGNIIGVGQCL---IYGLT-VVLRK 315

  Fly   257 PFAADYFVYLVSKYSITYALIPPEHC-------------CS-LLDCPTATPEKLGSLTKLNFGGG 307
            .|:|..|.....||:.|...:  .||             |. ||..|....|:...: :|..|.|
Human   316 KFSASRFWDDCIKYNCTINGV--RHCRLLCLVVQYIGEICRYLLKQPVREAERRHRV-RLAVGNG 377

  Fly   308 RMTQATVERVKKLAPNGV--LNSSYGMTE-----------VGFIVFNHGHLKLTAAGNPLPGIQ- 358
            .......|..::.   ||  :...||.||           ||...||         ...||.:.
Human   378 LRPAIWEEFTERF---GVRQIGEFYGATECNCSIANMDGKVGSCGFN---------SRILPHVYP 430

  Fly   359 ---VKIVDD------DGNQLGVN-QTGEIIVHNG--------FSWNGYFADPEATKAMQDEEGWF 405
               ||:.:|      |...|.:. |.||..:..|        ..::||.::...:|.:  ....|
Human   431 IRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDPLRRFDGYVSESATSKKI--AHSVF 493

  Fly   406 HTGDMGY-------FDEDDYLYMTDRKKEVLKWKGLQMWPAEVEAVIDELPEVKRVCVIGVYDET 463
            ..||..|       .||..|:|..||..:..:|:|..:...|||.|:..|.....|.|.||
Human   494 SKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEGVLSRLLGQTDVAVYGV---- 554

  Fly   464 QGDVPGALVVREDNATLTA----QQVIDHVAKRLPDIQKQLRAGVQFADEIPQNHNGKVVRRYAR 524
              .|||.    |..|.:.|    ..::|..|     |.::|:               ||:..|||
Human   555 --AVPGV----EGKAGMAAVADPHSLLDPNA-----IYQELQ---------------KVLAPYAR 593

  Fly   525 DLFVAL 530
            .:|:.|
Human   594 PIFLRL 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4830	NP_650160.1	CaiC	18..529	CDD:223395	128/588 (22%)
		AFD_class_I	46..518	CDD:302604	119/560 (21%)
SLC27A1	XP_011526302.1	PRK08279	42..656	CDD:236217	129/591 (22%)
		metallo-hydrolase-like_MBL-fold	64..>135	CDD:304873	12/72 (17%)
		AFD_class_I	101..623	CDD:302604	126/567 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149011
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840