Protein Alignment CG4830 and SLC27A1

DIOPT Version :10

• Sequence 1: NP_650160.1
• Gene: CG4830 / 41477
• FlyBaseID: FBgn0037996
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: XP_011526302.1
• Gene: SLC27A1 / 376497
• HGNCID: 10995
• Length: 658
• Species: Homo sapiens
• Alignment Length: 588
• Identity: 130/588 - (22%)
• Similarity: 204/588 - (34%)
• Gaps: 151/588 - (25%)

  Fly    29 SLGRIIFKNMRNWPKNVCQISDSEGVEVTFGQALTWAIRIAQQLKSRGLDHKDIIGISARNTTYI 93
            ::.||....::..|:.:..:....|...||.|...::..:|...:..|....|:
Human    77 TIPRIFQAVVQRQPERLALVDAGTGECWTFAQLDAYSNAVANLFRQLGFAPGDV----------- 130

  Fly    94 MPTAVACFFHGTP-------------FQSA--NPILEESTLKHLYNISKPKIIFTDADHYDKLYS 143
                ||.|..|.|             .::|  |..|....|......|..|.:....:....:..
Human   131 ----VAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALIFGGEMVAAVAE 191

  Fly   144 ATSAFKPEII-LTTGT--KDGVLSIQDLLAPTKTEFFYQPTPLKEGPSQ----TVAILTSSGTTG 201
            .:......:| ..:|.  .:|:|....||.|...|  ....||.:.||:    .:..:.:|||||
Human   192 VSGHLGKSLIKFCSGDLGPEGILPDTHLLDPLLKE--ASTAPLAQIPSKGMDDRLFYIYTSGTTG 254

  Fly   202 MPKAVCISNDILTQETVFVNG----------YDTIFISASLDWITGLWATIFSTVNGCTRIISSK 256
            :|||..:.:....:...|.:.          ||.:.:..|...|.|:...:   :.|.| ::..|
Human   255 LPKAAIVVHSRYYRMAAFGHHAYRMQAADVLYDCLPLYHSAGNIIGVGQCL---IYGLT-VVLRK 315

  Fly   257 PFAADYFVYLVSKYSITYALIPPEHC-------------CS-LLDCPTATPEKLGSLTKLNFGGG 307
            .|:|..|.....||:.|...:  .||             |. ||..|....|:...: :|..|.|
Human   316 KFSASRFWDDCIKYNCTINGV--RHCRLLCLVVQYIGEICRYLLKQPVREAERRHRV-RLAVGNG 377

  Fly   308 RMTQATVERVKKLAPNGV--LNSSYGMTE-----------VGFIVFNHGHLKLTAAGNPLPGIQ- 358
            .......|..::.   ||  :...||.||           ||...||         ...||.:.
Human   378 LRPAIWEEFTERF---GVRQIGEFYGATECNCSIANMDGKVGSCGFN---------SRILPHVYP 430

  Fly   359 ---VKIVDD------DGNQLGVN-QTGEIIVHNG--------FSWNGYFADPEATKAMQDEEGWF 405
               ||:.:|      |...|.:. |.||..:..|        ..::||.::...:|.:  ....|
Human   431 IRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDPLRRFDGYVSESATSKKI--AHSVF 493

  Fly   406 HTGDMGY-------FDEDDYLYMTDRKKEVLKWKGLQMWPAEVEAVIDELPEVKRVCVIGVYDET 463
            ..||..|       .||..|:|..||..:..:|:|..:...|||.|:..|.....|.|.||
Human   494 SKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEGVLSRLLGQTDVAVYGV---- 554

  Fly   464 QGDVPGALVVREDNATLTAQQVIDHVAKRLPD-IQKQLRAGVQFADEIPQNHNGKVVRRYARDLF 527
              .|||.    |..|.:.|  |.|..:...|: |.::|:               ||:..|||.:|
Human   555 --AVPGV----EGKAGMAA--VADPHSLLDPNAIYQELQ---------------KVLAPYARPIF 596

  Fly   528 VAL 530
            :.|
Human   597 LRL 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4830	NP_650160.1	Firefly_Luc_like	46..518	CDD:341237	120/557 (22%)
SLC27A1	XP_011526302.1	Adenylate forming domain, Class I superfamily	101..623	CDD:473059	127/564 (23%)