DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4830 and Acsm5

DIOPT Version :9

Sequence 1:	NP_650160.1	Gene:	CG4830 / 41477	FlyBaseID:	FBgn0037996	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	NP_001014184.3	Gene:	Acsm5 / 361637	RGDID:	1309578	Length:	578	Species:	Rattus norvegicus

Alignment Length:	474	Identity:	124/474 - (26%)
Similarity:	194/474 - (40%)	Gaps:	74/474 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 TAVACFFHGTPFQSANPILEESTLKHLYNISKPKIIFTD---ADHYDKLYSATSAFKPEIILTTG 157
            |.|||...|.........|.:..||:....::.|.|.|.   |.|.|.:.:...:.:..::::..
  Rat   130 TIVACMRTGVVMIPGISQLTQKDLKYRLQAARVKSIITSDALAPHVDAISADCPSLQSRLLVSDT 194

  Fly   158 TKDGVLSIQDLLAPTKTEFFYQPTPLKEGPSQTVAILTSSGTTGMPKAVCISN------------ 210
            ::.|.::.::||.....|.    ..|:.....::||..:|||||.||.|..|.
  Rat   195 SRPGWINFRELLRVASPEH----NCLRTRSGDSMAIYFTSGTTGTPKMVEHSQCSYGLGFVASGR 255

  Fly   211 --DILTQETVFVNGYDTIFISASLDWITGLWATIFST-VNGCTRIISSKP-FAADYFVYLVSKYS 271
              ..||:..:|.|..||       .|:...| |:||. .||....:...| ..|...:..:.::.
  Rat   256 RLMALTESDIFWNTTDT-------GWVKAAW-TLFSAWANGACVFVHELPQVDAQTILNTLCRFP 312

  Fly   272 ITYALIPPEHCCSLLDCPT----ATPEKLGSLTKLNF-------GGGRMTQATVERVKKLAPNGV 325
            ||..      ||    .||    ...|   .||:..|       .||....:.|....|......
  Rat   313 ITTI------CC----VPTLFRLLVQE---DLTRYKFQCLRHCLAGGEALNSDVRDKWKNQTGLE 364

  Fly   326 LNSSYGMTEVGFIV--FNHGHLKLTAAGNPLPGIQVKIVDDDGNQLGVNQTGEIIVH----NGFS 384
            ::..||.:|...|.  |....:|..:.|...|...|:|||::||.|...:.|.|.:.    ..|.
  Rat   365 IHEGYGQSETVLICGNFRGSTIKSGSMGKASPPYDVQIVDEEGNVLPPGKEGNIAIRIKPTRPFC 429

  Fly   385 -WNGYFADPEATKAMQDEEGWFH-TGDMGYFDEDDYLYMTDRKKEVLKWKGLQMWPAEVEAVIDE 447
             :|.|..:||.|.|  .|:|.|: |||..:.|||.|.:...|..:|:.....::.|.|||:.:.|
  Rat   430 LFNCYLDNPEKTAA--SEQGDFYITGDRAHMDEDGYFWFVGRNDDVINSSSYRIGPVEVESALAE 492

  Fly   448 LPEVKRVCVIGVYDETQGDVPGALV------VREDNATLTAQQVIDHVAKRLPDIQKQLRAGVQF 506
            .|.|....|:...|..:|:|..|.:      |..|...|| :::.:|| |.:....|..|. |.|
  Rat   493 HPAVLESAVVSSPDPIRGEVVKAFIVLSPAYVSHDPEALT-RELQEHV-KTVTAPYKYPRK-VAF 554

  Fly   507 ADEIPQNHNGKVVRRYARD 525
            ..|:|:..:||::|...|:
  Rat   555 ISELPKTVSGKILRSKLRN 573

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4830	NP_650160.1	CaiC	18..529	CDD:223395	124/474 (26%)
CG4830	NP_650160.1	AFD_class_I	46..518	CDD:302604	121/465 (26%)
Acsm5	NP_001014184.3	AFD_class_I	48..576	CDD:418409	124/474 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010