Protein Alignment CG4830 and ACSM4

DIOPT Version :9

• Sequence 1: NP_650160.1
• Gene: CG4830 / 41477
• FlyBaseID: FBgn0037996
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: NP_001073923.1
• Gene: ACSM4 / 341392
• HGNCID: 32016
• Length: 580
• Species: Homo sapiens
• Alignment Length: 512
• Identity: 129/512 - (25%)
• Similarity: 200/512 - (39%)
• Gaps: 66/512 - (12%)

  Fly    59 GQALTWAIRIAQQL---------KSRGLDHKDIIGISARNTTYIMP-------TAVACFFHGTPF 107
            |..:.|:.|....|         |..||...|.:.:       |:|       ..|||...|..|
Human    84 GDEVKWSFRELGSLSRKAANVLTKPCGLQRGDRLAV-------ILPRIPEWWLVNVACIRTGIIF 141

  Fly   108 QSANPILEESTLKHLYNISKPKIIFTD---ADHYDKLYSATSAFKPEIILTTGTKDGVLSIQDLL 169
            ......|....:.:....||.|.|...   |...:.:.......|.:::::..:.:|.||.|:|.
Human   142 MPGTIQLTAKDILYRLRASKAKCIVASEEVAPAVESIVLECPDLKTKLLVSPQSWNGWLSFQELF 206

  Fly   170 APTKTEFFYQPTPLKEGPSQTVAILTSSGTTGMPKAVCISNDILTQETVFVNGY-------DTIF 227
            .....|.    :.::.|..:.:.|..:|||||.||....|...|.........|       |.|:
Human   207 QFASEEH----SCVETGSQEPMTIYFTSGTTGFPKMAQHSQSSLGIGFTLCGRYWLDLKSSDIIW 267

  Fly   228 ISASLDWITGLWATIFST--VNGCTRIISSKPFAADYFVYLVSKYSITYALIPPEHCCSLLDCPT 290
            ..:...|:.....::||:  ...|..:.....|..|.|:..::.|.||....||. ...:|....
Human   268 NMSDTGWVKAAIGSVFSSWLCGACVFVHRMAQFDTDTFLDTLTTYPITTLCSPPT-VYRMLVQKD 331

  Fly   291 ATPEKLGSLTKLNFGGGRMTQATVERVKKLAPNGV-LNSSYGMTEVGFIVFNH--GHLKLTAAGN 352
            ....|..||.....||..:....:|:.:  ...|: |...||.||||.|..|.  ..:|..:.|.
Human   332 LKRYKFKSLRHCLTGGEPLNPEVLEQWR--VQTGLELYEGYGQTEVGMICANQKGQEIKPGSMGK 394

  Fly   353 PLPGIQVKIVDDDGNQLGVNQTGEIIVH----NGFS-WNGYFADPEATKAMQDEEGWFH-TGDMG 411
            .:....|:|:|::||.|...:.|||.:.    ..|. ::.|..:|:.|.|  ...|.|: |||.|
Human   395 GMLPYDVQIIDENGNVLPPGKEGEIALRLKPTRPFCFFSKYVDNPQKTAA--TIRGDFYVTGDRG 457

  Fly   412 YFDEDDYLYMTDRKKEVLKWKGLQMWPAEVEAVIDELPEVKRVCVIGVYDETQGDVPGALVV--- 473
            ..|.|.|.:...|..:|:...|.::.|.|||:.:.|.|.|....|:...|:.:|:|..|.||
Human   458 VMDSDGYFWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDQIRGEVVKAFVVLAA 522

  Fly   474 -----REDNATLTAQQVIDHVAKRLPDIQKQLRAGVQFADEIPQNHNGKVVRRYARD 525
                 ..:..||..|   |||.|.....:...:  |:|..|:|:...||:.|...||
Human   523 PFKSYNPEKLTLELQ---DHVKKSTAPYKYPRK--VEFVQELPKTITGKIKRNVLRD 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4830	NP_650160.1	CaiC	18..529	CDD:223395	129/512 (25%)
		AFD_class_I	46..518	CDD:302604	125/503 (25%)
ACSM4	NP_001073923.1	MACS_euk	48..577	CDD:213294	129/512 (25%)
		Acs	49..580	CDD:223442	129/512 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920