DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4830 and LOC316124

DIOPT Version :9

Sequence 1:	NP_650160.1	Gene:	CG4830 / 41477	FlyBaseID:	FBgn0037996	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	XP_006244385.1	Gene:	LOC316124 / 316124	RGDID:	1595856	Length:	705	Species:	Rattus norvegicus

Alignment Length:	578	Identity:	124/578 - (21%)
Similarity:	215/578 - (37%)	Gaps:	154/578 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 GVEVTFGQALTWAIRIAQQLKSRGLDHKDIIGISARNT----TYIMPTAVACFF---HGTPFQSA 110
            ||.:....:..|.|.....:.:.|:.    :||.:.|:    ..|..|:....|   :....|..
  Rat   129 GVGIMGINSSEWVIASIGAIMAGGIS----VGILSSNSPKACQIIAETSEMDIFVVDNDRQLQKV 189

  Fly   111 NPILEESTLKHLYNISKPKIIFTDADHYDKLYSATSAFKPEIILTTGTKDGVLSIQDLLAPTKTE 175
            |.|  :..||||      |.|....:...::.....::|           |.|.:.|.::..|.:
  Rat   190 NQI--QGYLKHL------KAIIQYREDIQEVQPNLYSWK-----------GFLDLADGISDEKLD 235

  Fly   176 FFYQPTPLKEGPSQTVAILTSSGTTGMPKAVCISNDIL---TQETVFVNGY------DTIFIS-- 229
            ....    .:.|:|..|::.:.||||.|||:.:|:|.:   |..||...||      ..|.:|
  Rat   236 QIID----AQKPNQCCALVYNQGTTGNPKAIMLSHDNITWTTAATVQSLGYKCPPHGQEILVSYL 296

  Fly   230 -------ASLD-WI--------------TGLWATIFSTVNG----------------C------T 250
                   ..|| |:              :|.|:.: ..|:|                |      .
  Rat   297 PLCFAGIQILDVWVAISVAGTVYFPSLESGKWSGL-PRVSGTGFLMELLREVQPTTFCGIPWVWD 360

  Fly   251 RIISS---KPFAADYFVYLVSKYSITYAL----------IPPEHCCSLLDCPTATPEK--LGSLT 300
            |::.|   |...:..|...:.::::...|          |....|..|....|..|.|  || |.
  Rat   361 RMLDSLKTKHLDSTAFRRKIDRWAMRMGLSTNKRQMMGGIHQPLCFGLAKRLTFKPAKKFLG-LN 424

  Fly   301 K----LNFGGGRMTQATVERVKKLAPNGVLNSSYGMTE-VGFIVFNH-GHLKLTAAGNPLPGIQV 359
            .    ||.|.| :.::|::..  |:.|..:...||::| .|....:. ...::.::|..||....
  Rat   425 HCEQFLNVGMG-LPRSTLDFF--LSMNIPILELYGLSECTGLHTLSSLQAYRILSSGKALPKTHT 486

  Fly   360 KIVDDDGNQLGVNQTGEIIVHNGFSWNGYFADPEATKAMQDEEGWFHTGDMGYFDEDDYLYMTDR 424
            |:  :..||.||   |.:.:.....:.||..|..:|:...|..||.||.|:|:.|.|.|||:|..
  Rat   487 KV--EKENQDGV---GNLCIWGRHVFMGYLRDKHSTERKVDNHGWLHTNDLGFLDFDKYLYVTGN 546

  Fly   425 KKEVLKWKGLQM---WPAEVEAVIDELPEVKRVCVIG---------------VYDETQGDVPGAL 471
            ..::::....:|   .|.| |.|...:|.|:...::|               :..|| |:..|.|
  Rat   547 TNDLIRLNSGEMVNPIPIE-ERVRTRIPLVRYAMLVGQDAPYLCALLTLKCQINPET-GEAQGNL 609

  Fly   472 V---------VREDNATLTAQQVIDHVAKRLPDIQKQLRAGVQFADEIPQNHNGKVVR 520
            .         :|..:..|:     |.:..|.|.:.:.:..|:|..:....:...|:::
  Rat   610 TSEAIACCRKLRSQSTWLS-----DVLYNRDPLVTQFIDQGIQDVNSEAPSVGAKIIK 662

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4830	NP_650160.1	CaiC	18..529	CDD:223395	124/578 (21%)
CG4830	NP_650160.1	AFD_class_I	46..518	CDD:302604	123/574 (21%)
LOC316124	XP_006244385.1	FAA1	74..701	CDD:223953	124/578 (21%)
LOC316124	XP_006244385.1	ACSBG_like	95..700	CDD:213299	124/578 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342984
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930