DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4830 and Acsm5

DIOPT Version :9

Sequence 1:	NP_650160.1	Gene:	CG4830 / 41477	FlyBaseID:	FBgn0037996	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	XP_006507967.1	Gene:	Acsm5 / 272428	MGIID:	2444086	Length:	591	Species:	Mus musculus

Alignment Length:	468	Identity:	125/468 - (26%)
Similarity:	197/468 - (42%)	Gaps:	64/468 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 AVACFFHGTPFQSANPILEESTLKHLYNISKPKIIFTD---ADHYDKLYSATSAFKPEIILTTGT 158
            :|||...|.........|....||:....::.|.|.|.   |...|.:.:...:.:.:::::..:
Mouse   144 SVACMRTGVVMIPGVSQLTAKDLKYRLQAARAKSIVTSDALAPQVDAISADCPSLQTKLLVSDTS 208

  Fly   159 KDGVLSIQDLLAPTKTEFFYQPTPLKEGPSQTVAILTSSGTTGMPKAVCISND------------ 211
            :.|.::.::||.....|  :.....:.|.|  |||..:|||||.||.|..|..
Mouse   209 RPGWINFRELLRAASPE--HNCVRTRSGDS--VAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRR 269

  Fly   212 --ILTQETVFVNGYDTIFISASLDWITGLWATIFST-VNGCTRIISSKP-FAADYFVYLVSKYSI 272
              .||:..:|.|..||       .|:...| |:||. .||....:...| ..|...:..:.::.|
Mouse   270 WMALTESDIFWNTTDT-------GWVKAAW-TLFSAWSNGACIFVHELPRVDAKTILNTLCRFPI 326

  Fly   273 TYALIPPEHCC-----SLLDCPTATPEKLGSLTKLNFGGGRMTQATVERVKKLAPNGV-LNSSYG 331
            |..      ||     .||.....|..|...|.....||..:.....::.|  :..|: |:..||
Mouse   327 TTL------CCVPTLFRLLVQEDLTRYKFQCLRHCLTGGEALNPDVRDKWK--SQTGLELHEGYG 383

  Fly   332 MTEVGFIVFN--HGHLKLTAAGNPLPGIQVKIVDDDGNQLGVNQTGEIIVH----NGFS-WNGYF 389
            .:|...|..|  :..:|..:.|...|...|:|||::||.|...:.|.|.|.    ..|. :|.|.
Mouse   384 QSETVVICGNSRNSTIKSGSMGKASPPYDVQIVDEEGNVLPPGKEGNIAVRIKPTRPFCFFNCYL 448

  Fly   390 ADPEATKAMQDEEGWFH-TGDMGYFDEDDYLYMTDRKKEVLKWKGLQMWPAEVEAVIDELPEVKR 453
            .:||.|.|  .|:|.|: |||..:.|||.|.:...|..:|:.....::.|.|||:.:.|.|.|..
Mouse   449 DNPEKTAA--SEQGDFYITGDRAHMDEDGYFWFLGRNDDVINSSSYRIGPVEVESALAEHPAVLE 511

  Fly   454 VCVIGVYDETQGDVPGALVV------REDNATLTAQQVIDHVAKRLPDIQKQLRAGVQFADEIPQ 512
            ..|:...|..:|:|..|.:|      ..|...|| :::.:|| |.:....|..|. |.|..|:|:
Mouse   512 SAVVSSPDPIRGEVVKAFIVLSPAYASHDPEALT-RELQEHV-KTVTAPYKYPRK-VAFISELPK 573

  Fly   513 NHNGKVVRRYARD 525
            ..:||::|...|:
Mouse   574 TVSGKILRSKLRN 586

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4830	NP_650160.1	CaiC	18..529	CDD:223395	125/468 (27%)
CG4830	NP_650160.1	AFD_class_I	46..518	CDD:302604	122/459 (27%)
Acsm5	XP_006507967.1	AFD_class_I	61..589	CDD:388389	125/468 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010