DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4830 and SPCC1827.03c

DIOPT Version :9

Sequence 1:	NP_650160.1	Gene:	CG4830 / 41477	FlyBaseID:	FBgn0037996	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	NP_001342732.1	Gene:	SPCC1827.03c / 2539253	PomBaseID:	SPCC1827.03c	Length:	512	Species:	Schizosaccharomyces pombe

Alignment Length:	536	Identity:	143/536 - (26%)
Similarity:	230/536 - (42%)	Gaps:	97/536 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 ISDSEGVEVTFGQALTWAIRIAQQLKSRGLDHKDIIGISARNTTYIMPTAVACFFHGTPFQSA-- 110
            ::.|...|::|.:.....:.:.:|:.|.|:...|.:.|:..|.   :...||  |:...:|.|
pombe    20 VAPSLNAELSFSELRIAIMDLQRQIASLGIKVGDPVNIAIPNG---LEFVVA--FYAVSWQRAIC 79

  Fly   111 ---NPILEESTLKHLYNISKPKIIF---------TDADHYDKLYS---ATSAFKPE-----IILT 155
               |...::|..:...:..|.|::.         |.|....|..|   |..|:.|:     |:..
pombe    80 GPLNSNYKQSEFEFYIDDLKSKLVIVPEGSVAANTPAVRAAKKLSVAVAELAWCPKSRLVRIVHF 144

  Fly   156 TGTKDGVLSIQDLLAPTKTEFFYQPTPLKEGPSQTVAILTSSGTTGMPKAVCISNDILTQE---- 216
            .|.|        :.||       ||..|.: |...:.:|.:|||||.||.|.:::..|.:.
pombe   145 EGAK--------INAP-------QPLGLPQ-PDDVMLVLHTSGTTGRPKVVPLTHKNLCRSIHNI 193

  Fly   217 --TVFVNGYDTIFISASLDWITGLWATIFSTV--NGCTRIISSKPFAADYFVYLVSKYSIT-YAL 276
              :..::..||.::...|..:.||...:.||:  .||. ::..| |:|..|.....:|..| |..
pombe   194 TTSYRLDPRDTSYVVMPLFHVHGLLCGLLSTLASGGCA-VVPPK-FSAHSFWKEFIQYGATWYTA 256

  Fly   277 IPPEHCCSLLDCPTATPEKLGSLTKLNFGGGRMTQATVERVKKL-----APNGVLNSSYGMTEVG 336
            :|..|.. ||..|...|     |.::.|.....:......:.||     ||  || .:|.|||.
pombe   257 VPTIHQI-LLRTPPPKP-----LPRIRFIRSCSSPLAPPVLSKLEATFRAP--VL-EAYAMTEA- 311

  Fly   337 FIVFNHGHLKLTAAGNPLP-------------GIQVKIVDDDGNQLGVNQTGEIIVHNGFSWNGY 388
                  .|...|   ||||             |:::||:|..||::...:.|||.|.......||
pombe   312 ------SHQMTT---NPLPPLVHKPHSVGKPFGVELKILDQKGNEMPQGKEGEICVRGINVTKGY 367

  Fly   389 FADPEATKAMQDEEGWFHTGDMGYFDEDDYLYMTDRKKEVLKWKGLQMWPAEVEAVIDELPEVKR 453
            ..:|.|.|:...::.:|.|||.|..|:|.|:::|.|.||::...|.::.|||::||:.:.|:|..
pombe   368 LNNPAANKSSFTKDRFFRTGDEGKLDKDGYVFITGRIKELVNRGGEKISPAEIDAVLMQHPDVSE 432

  Fly   454 VCVIGVYDETQGDVPGALVVREDNATLTAQQVIDHVAKRLP--DIQKQLRAGVQFADEIPQNHNG 516
            .....|.||..|....|.:......|:|.:|:.|::.:::.  .|.|:.    .|.|.||:...|
pombe   433 AVCFAVPDEKYGQDIQAAINPVAGKTVTPKQLHDYLEQKVAAFKIPKKF----YFTDRIPKTATG 493

  Fly   517 KVVRRYARDLFVALSK 532
            ||.||...|.|...||
pombe   494 KVQRRLVCDAFFNHSK 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4830	NP_650160.1	CaiC	18..529	CDD:223395	141/531 (27%)
CG4830	NP_650160.1	AFD_class_I	46..518	CDD:302604	135/520 (26%)
SPCC1827.03c	NP_001342732.1	FACL_fum10p_like	160..502	CDD:213292	106/366 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X778
TreeFam	0	0.000	Not matched by this tool.
	3	2.810