Protein Alignment CG4830 and DIP2A

DIOPT Version :9

• Sequence 1: NP_650160.1
• Gene: CG4830 / 41477
• FlyBaseID: FBgn0037996
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: XP_011527794.1
• Gene: DIP2A / 23181
• HGNCID: 17217
• Length: 1607
• Species: Homo sapiens
• Alignment Length: 582
• Identity: 117/582 - (20%)
• Similarity: 193/582 - (33%)
• Gaps: 165/582 - (28%)

  Fly    65 AIRIAQQLKSRGL----DHKDII---GISARNTTYIMPTAVACFFHGTPFQSANPILEES----- 117
            |.|:|..|..:|.    ||..::   |:.      ::.....|.:.|....:..|...::
Human  1062 AERVAAALMEKGRLSVGDHVALVYPPGVD------LIAAFYGCLYCGCVPVTVRPPHPQNLGTTL 1120

  Fly   118 -TLKHLYNISKPKIIFTDADHYDKLYSATSAFKPEIILTTGTKDGVLSIQDLLAPTKTEFFYQPT 181
             |:|.:..:||...:.|.......|.|..:|...:|    .|...:|...|:........|..|:
Human  1121 PTVKMIVEVSKSACVLTTQAVTRLLRSKEAAAAVDI----RTWPTILDTDDIPKKKIASVFRPPS 1181

  Fly   182 PLKEGPSQTVAILT-SSGTTGM----------PKAVCISNDILTQETVFVNGYDTIFISASLDWI 235
            |      ..:|.|. |..|||:          ..|:|.|..:..:.      |.:..|:..||..
Human  1182 P------DVLAYLDFSVSTTGILAGVKMSHAATSALCRSIKLQCEL------YPSRQIAICLDPY 1234

  Fly   236 TG----LWATIFSTVNGCTRIISSKPFAADYFVYL----VSKYS-----ITYALIPPEHCCSLLD 287
            .|    ||. :.|..:|...:: ..|...:..|.|    ||:|.     .:|:::  |.|...|.
Human  1235 CGLGFALWC-LCSVYSGHQSVL-VPPLELESNVSLWLSAVSQYKARVTFCSYSVM--EMCTKGLG 1295

  Fly   288 CPTATPEKLGSLTKLNFGGGRMTQATVERVKKLA--------------PNGVLNSSYG------- 331
            ..|......|    :|....|......|...::|              |...:::::|
Human  1296 AQTGVLRMKG----VNLSCVRTCMVVAEERPRIALTQSFSKLFKDLGLPARAVSTTFGCRVNVAI 1356

  Fly   332 -----------MTEVGFIVFNHGHLKLTAAGNP-----------LPGIQVKIV-DDDGNQLGVNQ 373
                       ...|......|..::|...|:|           |||::|.|. .:....||.:.
Human  1357 CLQGTAGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVKVIIAHTETKGPLGDSH 1421

  Fly   374 TGEIIVHNGFSWNGYF---------ADP-EATKAMQDEEG-WFHTGDMGYF----------DEDD 417
            .|||.|.:..:..||:         ||. .|..:..|.:. |..||.:|:.          ...|
Human  1422 LGEIWVSSPHNATGYYTVYGEEALHADHFSARLSFGDTQTIWARTGYLGFLRRTELTDASGGRHD 1486

  Fly   418 YLYMTDRKKEVLKWKGLQMWPAEVEAVIDELPEVKRVCVIGVYD-------ETQGDVPGAL---- 471
            .||:.....|.|:.:|::..|.::|..:.........|.:..:.       |..|....||
Human  1487 ALYVVGSLDETLELRGMRYHPIDIETSVIRAHRSIAECAVFTWTNLLVVVVELDGLEQDALDLVA 1551

  Fly   472 ----VVREDNATLTAQQVIDHVAKRLPDIQKQLRAGVQFADEIPQNHNGKVVRRYARDLFVA 529
                ||.|::..:....||             :..||     ||.|..|:..|.:.||.|:|
Human  1552 LVTNVVLEEHYLVVGVVVI-------------VDPGV-----IPINSRGEKQRMHLRDGFLA 1595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4830	NP_650160.1	CaiC	18..529	CDD:223395	116/580 (20%)
		AFD_class_I	46..518	CDD:302604	112/569 (20%)
DIP2A	XP_011527794.1	DMAP_binding	9..158	CDD:283995
		CaiC	360..959	CDD:223395
		AFD_class_I	392..956	CDD:302604
		AMP-binding	1027..1501	CDD:278902	93/468 (20%)
		AFD_class_I	1044..1596	CDD:302604	117/582 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900