Protein Alignment CG4830 and DIP2C

DIOPT Version :9

• Sequence 1: NP_650160.1
• Gene: CG4830 / 41477
• FlyBaseID: FBgn0037996
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: XP_011517730.1
• Gene: DIP2C / 22982
• HGNCID: 29150
• Length: 1626
• Species: Homo sapiens
• Alignment Length: 586
• Identity: 121/586 - (20%)
• Similarity: 201/586 - (34%)
• Gaps: 163/586 - (27%)

  Fly    65 AIRIAQQLKSRGL----DHKDII---GISARNTTYIMPTAVACFFHG------TPFQSANPILEE 116
            |.:||..|..||.    ||..::   ||.      ::.....|.:.|      .|....|.....
Human  1071 AEKIAVMLMERGHLQDGDHVALVYPPGID------LIAAFYGCLYAGCVPITVRPPHPQNIATTL 1129

  Fly   117 STLKHLYNISKPKIIFTDADHYDKLYSATSAFKPEIILTTGTKDGVLSIQDLLAPTKTEFFYQPT 181
            .|:|.:..:|:...:.|.......|.|..:|...::    .|...:|...||  |.|     :|.
Human  1130 PTVKMIVEVSRSACLMTTQLICKLLRSREAAAAVDV----RTWPLILDTDDL--PKK-----RPA 1183

  Fly   182 PL-KEGPSQTVAILT-SSGTTGMPKAVCISNDILTQETVFVNG-------YDTIFISASLDWITG 237
            .: |.....|:|.|. |..||||...|.:|:   ...:.|...       |.:..::..||...|
Human  1184 QICKPCNPDTLAYLDFSVSTTGMLAGVKMSH---AATSAFCRSIKLQCELYPSREVAICLDPYCG 1245

  Fly   238 ----LWATIFSTVNGCTRII---SSKPFAADYFVYLVSKYSI-----TYALIPPEHCCSLLDCPT 290
                ||. :.|..:|...|:   |........::..||:|.:     :|:::  |.|...|...|
Human  1246 LGFVLWC-LCSVYSGHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVM--ELCTKGLGSQT 1307

  Fly   291 ATPEKLG-----------------------SLTKL--NFG----------GGRMTQATV---ERV 317
            .:.:..|                       |.:||  :.|          |.|:..|..   .|:
Human  1308 ESLKARGLDLSRVRTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQPHRL 1372

  Fly   318 KKLAPNGVLNSSYGMTEVGFIVFNHGHLKLTAAGNP-----------LPGIQVKIVD-DDGNQLG 370
            ..||..|..........|......|..::|...|:|           |||:::.|.: :....||
Human  1373 WTLAEQGTSGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLG 1437

  Fly   371 VNQTGEIIVHNGFSWNGYFADPEATKAMQDEEG------------WFHTGDMGYF---------- 413
            .:..|||.||:..:.:|||. ....:::|.:..            |..||.:|:.
Human  1438 DSHLGEIWVHSAHNASGYFT-IYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANG 1501

  Fly   414 DEDDYLYMTDRKKEVLKWKGLQMWPAEVEAVIDELPEVKRVCVIGVYD-------ETQGDVPGAL 471
            :..|.||:.....|.::.:|::..|.::|..:....:....|.:..:.       |..|....||
Human  1502 ERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVELDGSEQEAL 1566

  Fly   472 --------VVREDNATLTAQQVIDHVAKRLPDIQKQLRAGVQFADEIPQNHNGKVVRRYARDLFV 528
                    ||.|::..:....|:..:             ||     ||.|..|:..|.:.||.|:
Human  1567 DLVPLVTNVVLEEHYLIVGVVVVVDI-------------GV-----IPINSRGEKQRMHLRDGFL 1613

  Fly   529 A 529
            |
Human  1614 A 1614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4830	NP_650160.1	CaiC	18..529	CDD:223395	120/584 (21%)
		AFD_class_I	46..518	CDD:302604	116/573 (20%)
DIP2C	XP_011517730.1	DMAP_binding	<32..180	CDD:283995
		CaiC	377..968	CDD:223395
		Dip2	401..965	CDD:213273
		AMP-binding	1036..1520	CDD:278902	98/472 (21%)
		AFD_class_I	1053..1615	CDD:302604	121/586 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900