Protein Alignment CG4830 and ACSL4

DIOPT Version :9

• Sequence 1: NP_650160.1
• Gene: CG4830 / 41477
• FlyBaseID: FBgn0037996
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: XP_024308119.1
• Gene: ACSL4 / 2182
• HGNCID: 3571
• Length: 717
• Species: Homo sapiens
• Alignment Length: 630
• Identity: 140/630 - (22%)
• Similarity: 215/630 - (34%)
• Gaps: 173/630 - (27%)

  Fly    18 IPQNNPFKPETSLGRIIFKNMRNWPKNVCQISDSEGVEVTFGQALTWAIRIAQQLKSRGLDHKDI 82
            :.:.|..:|...:.:.:......| .|..:::....   .||..||          :.||..|:.
Human   108 LSEENEMQPNGKVFKKLILGNYKW-MNYLEVNRRVN---NFGSGLT----------ALGLKPKNT 158

  Fly    83 IGISARNTTYIMPTAVACFFHGTPFQSANPILEESTLKHLYNISKPKIIFTDADHYDKLYSATSA 147
            |.|........|..|..||.:..|..:....|.:..:.|..|.|:...:.|..:
Human   159 IAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVE----------- 212

  Fly   148 FKPEIILTTGTKDGVLSIQ--------DLLAPTKTEFFYQP-----------------------T 181
                 :|.:..|..:|.|.        |..|..|.|:   |                       .
Human   213 -----LLESKLKTALLDISCVKHIIYVDNKAINKAEY---PEGFEIHSMQSVEELGSNPENLGIP 269

  Fly   182 PLKEGPSQTVAILTSSGTTGMPKAVCI--SNDI--LTQETVFVNGY---DTIFISASLDWITGLW 239
            |.:..||....::.:||:||.||.|.:  ||.|  :|.:...:.|.   ||......|..:..|.
Human   270 PSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELT 334

  Fly   240 ATIFSTVNGCTRIISSKPFAADYFVYLVSKYSITYALIPPEHCCSLLDCPT---ATPEKLGSLTK 301
            |.|.....|| ||..|.|.........:.|.|        :..|::|. ||   |.||.:..:.|
Human   335 AEISCFTYGC-RIGYSSPLTLSDQSSKIKKGS--------KGDCTVLK-PTLMAAVPEIMDRIYK 389

  Fly   302 --------LNFGGGRMTQAT---------VERVKK------------------------------ 319
                    :|:     .|.|         :|::||
Human   390 NVMSKVQEMNY-----IQKTLFKIGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGG 449

  Fly   320 --LAPNG----------VLNSSYGMTE---VGFIV----FNHGHLKLTAAGNPLPGIQVKIVD-- 363
              |:|..          .:...||:||   .|.:.    :..|.:     |.||...::|:.|
Human   450 APLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRV-----GAPLICCEIKLKDWQ 509

  Fly   364 DDGNQLG--VNQTGEIIVHNGFSWNGYFADPEATKA--MQDEEG--WFHTGDMGYFDEDDYLYMT 422
            :.|..:.  .|..|||::.......|||.:.|.|..  ..||.|  ||.|||:|.|..|..|.:.
Human   510 EGGYTINDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQII 574

  Fly   423 DRKKEVLKWK-GLQMWPAEVEAVIDELPEVKRVCVIGVYDETQGDVPGALVVREDNATLTAQQVI 486
            ||||:::|.: |..:...:|||.:...|.:..:|.....|  |..|...:|..:...||.|||
Human   575 DRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSD--QSYVISFVVPNQKRLTLLAQQ-- 635

  Fly   487 DHVAKRLPDIQKQLRAGVQFADEIPQNHNGKVVRRYARDLFVALS 531
            ..|.....||........:...||.:..|...:.|:...:.|.||
Human   636 KGVEGTWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLS 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4830	NP_650160.1	CaiC	18..529	CDD:223395	137/626 (22%)
		AFD_class_I	46..518	CDD:302604	132/587 (22%)
ACSL4	XP_024308119.1	LC-FACS_euk	127..714	CDD:213293	138/611 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148967
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930