Protein Alignment CG4830 and ACSL3

DIOPT Version :10

• Sequence 1: NP_650160.1
• Gene: CG4830 / 41477
• FlyBaseID: FBgn0037996
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: NP_004448.2
• Gene: ACSL3 / 2181
• HGNCID: 3570
• Length: 720
• Species: Homo sapiens
• Alignment Length: 532
• Identity: 115/532 - (21%)
• Similarity: 185/532 - (34%)
• Gaps: 129/532 - (24%)

  Fly    20 QNNPFKPETSLGRIIFKNMRNWPKNVCQISDSEGVEVTFGQALTWAIRIAQQLKSRGLDHKDIIG 84
            :.:..:|...:.:.:.....||              :::......|......|:..|...|..|.
Human   113 EEDEVQPNGKIFKKVILGQYNW--------------LSYEDVFVRAFNFGNGLQMLGQKPKTNIA 163

  Fly    85 ISARNTTYIMPTAVACFFHGTPFQSANPILEESTLKHLYNISKPKIIFTDADHYDKLYSATSAFK 149
            |........|..|.|||.:.....:....|....:.|..|.::...|.|..:..........:..
Human   164 IFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLV 228

  Fly   150 PEI--ILTTGTK--------DGVL-----SIQDLLAPTKTEFFYQPTPLKEGPSQTVAILTSSGT 199
            |.:  |:|...|        .|::     :::.|.|....|......||   ||....|:.:||:
Human   229 PRLRHIITVDGKPPTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPL---PSDIAVIMYTSGS 290

  Fly   200 TGMPKAVCISND--------------ILTQETVFVNGYDTIFISASLDWITGLWATIFSTVNGCT 250
            ||:||.|.||:.              .|.:|.|:: ||      ..|..:..|.|.:....:||.
Human   291 TGLPKGVMISHSNIIAGITGMAERIPELGEEDVYI-GY------LPLAHVLELSAELVCLSHGCR 348

  Fly   251 RIISSKPFAADYFVYL-------VSKYSITYALIPPEHCCSLLD--------------------- 287
            ...||....||....:       .|....|.....||    ::|
Human   349 IGYSSPQTLADQSSKIKKGSKGDTSMLKPTLMAAVPE----IMDRIYKNVMNKVSEMSSFQRNLF 409

  Fly   288 -------------------CPTATPEK----LGSLTKLNFGGGRMTQATVERVKKLAPNGVLNSS 329
                               |.:....|    ||...:|...||....||.:|...:.....:...
Human   410 ILAYNYKMEQISKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQG 474

  Fly   330 YGMTE---VGFIV----FNHGHLKLTAAGNPLPGIQVKIVD-DDGNQLGVNQ---TGEIIVHNGF 383
            ||:||   .|.|.    :|.|.:     |.||...::|:.: ::|.....::   .|||::....
Human   475 YGLTESAGAGTISEVWDYNTGRV-----GAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQS 534

  Fly   384 SWNGYFADPEATKA--MQDEEG--WFHTGDMGYFDEDDYLYMTDRKKEVLKWK-GLQMWPAEVEA 443
            ...||:.:...|||  .:||.|  |..|||:|.|:.|..|.:.||||:::|.: |..:...:|||
Human   535 VTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVEA 599

  Fly   444 VIDELPEVKRVC 455
            .:..||.|..:|
Human   600 ALKNLPLVDNIC 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4830	NP_650160.1	Firefly_Luc_like	46..518	CDD:341237	112/506 (22%)
ACSL3	NP_004448.2	Adenylate forming domain, Class I superfamily	30..717	CDD:473059	115/532 (22%)