Protein Alignment CG4830 and ACSL1

DIOPT Version :10

• Sequence 1: NP_650160.1
• Gene: CG4830 / 41477
• FlyBaseID: FBgn0037996
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: NP_001986.2
• Gene: ACSL1 / 2180
• HGNCID: 3569
• Length: 698
• Species: Homo sapiens
• Alignment Length: 547
• Identity: 113/547 - (20%)
• Similarity: 188/547 - (34%)
• Gaps: 138/547 - (25%)

  Fly     8 YDAENKIWKG------IPQNNPF----KPETSLGRIIFKNMRNWPKNVCQISDSEGVEVTFGQAL 62
            ||....:::|      :..|.|.    ||:.....:.:       |.|.::|:      ..|.||
Human    86 YDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEWLSY-------KQVAELSE------CIGSAL 137

  Fly    63 TWAIRIAQQLKSRGLDHKDIIGISARNTTYIMPTAVACFFHGTPFQSANPILEESTLKHLYNISK 127
                 |.:..|:.   ....|||.|:|....:.....||.:..........|....:.::.|.::
Human   138 -----IQKGFKTA---PDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAE 194

  Fly   128 PKIIFTDADHYDKL---------------YSATSAFKPEIILTTGTKDGV-----LSIQDLLAPT 172
            ..::|.|.....||               .....|:..|:: ..|.:.||     .:::||....
Human   195 LSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELV-ERGQRCGVEVTSMKAMEDLGRAN 258

  Fly   173 KTEFFYQPTPLKEGPSQTVAILTSSGTTGMPKAVCISN-DILTQETVFVNGY---------DTIF 227
            :.:      |....|.....|..:|||||.||...::: :|::..:.||...         ||:.
Human   259 RRK------PKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLI 317

  Fly   228 ------------------------------ISASLDWITGLWATIFSTVNGCTRII--------- 253
                                          |...:|.:..|..|:|..|   .|::
Human   318 SFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQPTVFPVV---PRLLNRMFDRIFG 379

  Fly   254 -------------SSKPFAADYFVYLVSKYSITYALIPPEHCCSLLDCPTATPEKLGSLTKLNFG 305
                         :||...|:....::...|:...||..:           ....||...:|...
Human   380 QANTTLKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHK-----------VQSSLGGRVRLMVT 433

  Fly   306 GGRMTQATVERVKKLAPNGVLNSSYGMTE--VGFIVFNHGHLKLTAAGNPLPGIQVKIVD-DDGN 367
            |.....|||....:.|........||.||  .|..:...|.......|.|:|...:|:|| ::.|
Human   434 GAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMN 498

  Fly   368 QLGVNQTGEIIVHNGFSWNGYFADPEATKAMQDEEGWFHTGDMGYFDEDDYLYMTDRKKEVLKW- 431
            .:.....||:.|.....:.||..||..|....|::||.||||:|.:..:..|.:.||||.:.|.
Human   499 YMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLA 563

  Fly   432 KGLQMWPAEVEAVIDELPEVKRVCVIG 458
            :|..:.|.::|.:......|.:|.|.|
Human   564 QGEYIAPEKIENIYMRSEPVAQVFVHG 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4830	NP_650160.1	Firefly_Luc_like	46..518	CDD:341237	104/499 (21%)
ACSL1	NP_001986.2	LC-FACS_euk	116..694	CDD:341250	106/517 (21%)