Protein Alignment CG4830 and ACSM2A

DIOPT Version :9

• Sequence 1: NP_650160.1
• Gene: CG4830 / 41477
• FlyBaseID: FBgn0037996
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: NP_001295101.1
• Gene: ACSM2A / 123876
• HGNCID: 32017
• Length: 577
• Species: Homo sapiens
• Alignment Length: 540
• Identity: 123/540 - (22%)
• Similarity: 211/540 - (39%)
• Gaps: 123/540 - (22%)

  Fly    59 GQALTWAIRIAQQLKSR---------GLDHKDIIGISARNTTYIMP-------TAVACFFHGTPF 107
            |:.|.|..|...:...:         ||...|.:.:       ::|       ..:.|...|..|
Human    76 GKELMWNFRELSENSQQAANVLSGACGLQRGDRVAV-------VLPRVPEWWLVILGCIRAGLIF 133

  Fly   108 QSANPILEESTLKHLYNISKPKIIFTDAD---HYDKLYSATSAFKPEIILTTGTKDGVLSIQDLL 169
            ......::.:.:.:...:||.|.|....:   ..|.:.|...:.:.:::::..:.||.|:.:.||
Human   134 MPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLL 198

  Fly   170 APTKTEFFYQPTPLKEGPSQTVAILTSSGTTGMPKAVCISNDILTQETVFVNGYDTIFISASLD- 233
            ....|......|    |..:..||..:|||:|:||             :..:.|.::.:.|.:|
Human   199 NEASTTHHCVET----GSQEASAIYFTSGTSGLPK-------------MAEHSYSSLGLKAKMDA 246

  Fly   234 -WITGLWAT-IFSTVNGCTRIIS-----SKPFA--ADYFVYLVSKYS------------------ 271
             | |||.|: |..|::....|::     .:|:|  |..||:|:.|:.
Human   247 GW-TGLQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTLSSYPIKSMMG 310

  Fly   272 --ITYALIPPEHCCS-----LLDCPTATPEKLGSLTKLNFGGGRMTQATVERVKKLAPNGV-LNS 328
              |.|.::..:...|     |.:|.|.              |..:...|:|..:  |..|: :..
Human   311 APIVYRMLLQQDLSSYKFPHLQNCVTV--------------GESLLPETLENWR--AQTGLDIRE 359

  Fly   329 SYGMTEVGFIVFNHGHLKLTAA--GNPLPGIQVKIVDDDGNQLGVNQTGEI------IVHNGFSW 385
            |||.||.|........:|:...  |.......|:|:||.||.|.....|:|      |...|. :
Human   360 SYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIIDDKGNVLPPGTEGDIGIRVKPIRPIGI-F 423

  Fly   386 NGYFADPEATKAMQDEEGWFHTGDMGYFDEDDYLYMTDRKKEVLKWKGLQMWPAEVEAVIDELPE 450
            :||..:|:.|.|....:.|. .||.|..|||.|.....|..:::...|.::.|:|||..:.|.|.
Human   424 SGYVDNPDKTAANIRGDFWL-LGDRGIKDEDGYFQFMGRANDIINSSGYRIGPSEVENALMEHPA 487

  Fly   451 VKRVCVIGVYDETQGDVPGALVVREDNATLTAQQVIDHVAKRL-PDIQKQLRA---------GVQ 505
            |....||...|..:|:|..|.||       .|.|.:.|..::| .::|:.:::         .::
Human   488 VVETAVISSPDPVRGEVVKAFVV-------LASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIE 545

  Fly   506 FADEIPQNHNGKVVRRYARD 525
            |...:|:...||:.|...||
Human   546 FVLNLPKTVTGKIQRAKLRD 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4830	NP_650160.1	CaiC	18..529	CDD:223395	123/540 (23%)
		AFD_class_I	46..518	CDD:302604	119/531 (22%)
ACSM2A	NP_001295101.1	AFD_class_I	40..568	CDD:388389	123/540 (23%)
		Coenzyme A binding. /evidence=ECO:0000269|PubMed:19345228	469..471		0/1 (0%)
		Coenzyme A binding. /evidence=ECO:0000269|PubMed:19345228	540..542		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920