DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4830 and Acsl3

DIOPT Version :9

Sequence 1:	NP_650160.1	Gene:	CG4830 / 41477	FlyBaseID:	FBgn0037996	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	NP_476448.1	Gene:	Acsl3 / 114024	RGDID:	70552	Length:	720	Species:	Rattus norvegicus

Alignment Length:	543	Identity:	120/543 - (22%)
Similarity:	194/543 - (35%)	Gaps:	137/543 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 NPFKPETSLGR--------------IIFKNM----RNWPKNVCQISDSEGVEVTFGQALTWAIRI 68
            |.||.:..||.              .:||.:    .||              :::......|:..
  Rat    97 NKFKDKRLLGTREILNEEDEIQPNGKVFKKVILGHYNW--------------LSYEDVFIRALDF 147

  Fly    69 AQQLKSRGLDHKDIIGISARNTTYIMPTAVACFFHGTPFQSANPILEESTLKHLYNISKPKIIFT 133
            ...|:..|...|..|.|........|..|.|||.:.....:....|....:.|..|.::...|.|
  Rat   148 GNGLQMLGQKPKANIAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHGLNETEVTNIIT 212

  Fly   134 DADHYDKLYSATSAFKPEI--ILTTGTK--------DGVL-----SIQDLLAPTKTEFFYQPTPL 183
            ..:..........:..|.:  |:|...|        .||:     ::|.|......:......||
  Rat   213 SKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSEFPKGVIVHTMAAVQALGVKADVDKKAHSKPL 277

  Fly   184 KEGPSQTVAILTSSGTTGMPKAVCIS-NDILTQETVFVN-----GYDTIFIS-ASLDWITGLWAT 241
               ||....|:.:||:||:||.|.|| ::|:...|....     |.:.::|. ..|..:..|.|.
  Rat   278 ---PSDIAVIMYTSGSTGIPKGVMISHSNIIASITGMARRIPRLGEEDVYIGYLPLAHVLELSAE 339

  Fly   242 IFSTVNGCTRIISSKPFAADYFVYL---------VSKYSITYALIPPEHCCSLLD---------- 287
            :....:||....||....||....:         |.|.::..|:  ||    ::|
  Rat   340 LVCLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSVLKPTLMAAV--PE----IMDRIYKNVMNKV 398

  Fly   288 -------------------------CPTATPEK---------LGSLTKLNFGGGRMTQATVERVK 318
                                     |.|...::         ||...::...||....||.:|..
  Rat   399 NEMSAFQRNLFILAYNYKMEQISKGCSTPLCDRFVFRNVRRLLGGNIRVLLCGGAPLSATTQRFM 463

  Fly   319 KLAPNGVLNSSYGMTE---VGFIV----FNHGHLKLTAAGNPLPGIQVKIVD-DDGNQLGVNQ-- 373
            .:.....:...||:||   .|.|.    :|.|.:     |.||...::|:.: ::|.....::
  Rat   464 NICFCCPVGQGYGLTESTGAGTITEVWDYNTGRV-----GAPLVCCEIKLKNWEEGGYFNTDKPH 523

  Fly   374 -TGEIIVHNGFSWNGYFADPEATKA--MQDEEG--WFHTGDMGYFDEDDYLYMTDRKKEVLKWK- 432
             .|||::.......||:.:...|||  .:||.|  |..|||:|.||.|..|.:.||||:::|.:
  Rat   524 PRGEILIGGQNVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFDPDGCLKIIDRKKDLVKLQA 588

  Fly   433 GLQMWPAEVEAVIDELPEVKRVC 455
            |..:...:|||.:..||.:..:|
  Rat   589 GEYVSLGKVEAALKNLPLIDNIC 611

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4830	NP_650160.1	CaiC	18..529	CDD:223395	120/543 (22%)
CG4830	NP_650160.1	AFD_class_I	46..518	CDD:302604	111/501 (22%)
Acsl3	NP_476448.1	PLN02387	30..717	CDD:215217	120/543 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342956
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930