DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4830 and acsm3

DIOPT Version :9

Sequence 1:	NP_650160.1	Gene:	CG4830 / 41477	FlyBaseID:	FBgn0037996	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	XP_002932029.3	Gene:	acsm3 / 100491087	XenbaseID:	XB-GENE-486978	Length:	581	Species:	Xenopus tropicalis

Alignment Length:	596	Identity:	134/596 - (22%)
Similarity:	222/596 - (37%)	Gaps:	137/596 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 GIPQN-----------NPFKPETSLGRIIFKNMRN-----WPKNVCQISDSEGVEVTF----GQA 61
            |.|||           .|..||       :.|..|     |..|..:...|....:.:    |:.
Frog    30 GTPQNFSNYEDIKLNYKPKVPE-------YFNFANDIIDEWAINRKEAGKSSNPALWWIDGSGEE 87

  Fly    62 LTWAIRIAQQLKSRGLDHKDIIGISARNTTYIMPTA-----------------------VACFFH 103
            :.|:.              :.:|..:|....::..|                       |||...
Frog    88 VKWSF--------------EELGFLSRKAANVLSDACNLKPGDRVIVILPRVPEWWLLNVACIRA 138

  Fly   104 GTPFQSANPILEESTLKHLYNISKPKIIFTD---ADHYDKLYSATSAFKPEIILTTGTKDGVLSI 165
            |.........|....:.|....|..|.|.|.   .:..|.:.:.:...:.:::::|..:||.|..
Frog   139 GVVLIPGTTQLTAKDILHRLQTSMAKCIITSDCLVEAVDSVAAQSPFLQTKMLISTERRDGWLDF 203

  Fly   166 QDLLAPTKTEFFYQPTPLKEGPSQTVAILTSSGTTGMPKAVCISNDILTQET-------VFVNG- 222
            :.|......:.    |.:|...|..:.|..:|||||.||        :|:.:       :.|||
Frog   204 KGLFQVANDKH----TCVKTKSSDPMTIFFTSGTTGSPK--------MTEHSHCSYGLGLKVNGK 256

  Fly   223 -------YDTIFISASLDWITGLWATIFST-VNGCTRIISSKP-FAADYFVYLVSKYSITYALIP 278
                   .|.::..:...|....|:::|:. :.|......|.| |..:..:..:|.:.||
Frog   257 YWMDLTPTDIVWNMSDTGWAKSAWSSVFAPWIQGSCVFAHSMPRFDTNIVLKTLSTFPIT----- 316

  Fly   279 PEHCCSLLDCPTA---------TPEKLGSLTKLNFGGGRMTQATVERVKKLAPNGV-LNSSYGMT 333
                 :....|||         ...|..||......|..:....:|:.|:  ..|: :...||.|
Frog   317 -----TFCSAPTAYRMLVLQNFASYKFKSLQHCVSAGEPINPQVMEQWKE--QTGLDIYEGYGQT 374

  Fly   334 EVGFI--VFNHGHLKLTAAGNPLPGIQVKIVDDDGNQLGVNQTGEIIV----HNGFS-WNGYFAD 391
            |...|  .|....:|..:.|.|.|...|:|||::||.|...:.|:|.:    ...|. ::.|..|
Frog   375 ETVLICGTFKGMKIKPGSMGKPSPAYDVEIVDENGNVLPQGKEGDIAIRILPQKPFCLFSQYTGD 439

  Fly   392 PEATKAMQDEEGWFH-TGDMGYFDEDDYLYMTDRKKEVLKWKGLQMWPAEVEAVIDELPEVKRVC 455
            ||.|.:.:  .|.|: |||.|..|||.|.:...|..:|:...|.::.|.|||:.:.|.|.|....
Frog   440 PERTASTR--RGNFYLTGDRGIKDEDGYFWFVGRSDDVILSSGYRIGPFEVESALIEHPAVAESA 502

  Fly   456 VIGVYDETQGDVPGALVVRE------DNATLTAQQVIDHVAKRLPDIQKQLRAGVQFADEIPQNH 514
            |:...|..:|:|..|.||..      |...| |.::.:|| :.:....|..|. ::|..::|:..
Frog   503 VVSSPDPIRGEVVKAFVVLAPAYNGYDPEKL-ALELQEHV-RNITAPYKYPRK-IEFVQQLPKTV 564

  Fly   515 NGKVVRRYARD 525
            :||:.|...|:
Frog   565 SGKIRRNELRN 575

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4830	NP_650160.1	CaiC	18..529	CDD:223395	133/595 (22%)
CG4830	NP_650160.1	AFD_class_I	46..518	CDD:302604	120/542 (22%)
acsm3	XP_002932029.3	MACS_euk	49..578	CDD:341251	129/577 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920