DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3d2 and AT5G44320

DIOPT Version :9

Sequence 1:	NP_731675.1	Gene:	eIF3d2 / 41475	FlyBaseID:	FBgn0037994	Length:	551	Species:	Drosophila melanogaster
Sequence 2:	NP_199245.1	Gene:	AT5G44320 / 834457	AraportID:	AT5G44320	Length:	588	Species:	Arabidopsis thaliana

Alignment Length:	586	Identity:	225/586 - (38%)
Similarity:	336/586 - (57%)	Gaps:	74/586 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 VEYNEHGWGPCEVPEL------------DVPYQPFCKSDRLGKICDWTAMVPEKKFPSKYASTFG 64
            |.:|..||||.:..:.            :||:..|.:|::||::.|||..:..   ||....| |
plant    11 VPFNSDGWGPPDASDTSSTSVAAANLLPNVPFASFSRSEKLGRVADWTRALSN---PSARPHT-G 71

  Fly    65 NNSQYAYFYE-------------------DDDSTFHLVDTTGSKATKPYQRGRYRPNMR-NNVRS 109
            :.|..:..::                   |:|:.|.|||      .||..|.::.|..| |...:
plant    72 SKSDPSAIFDFSAFAVDEGFGLTNSGGNADEDAAFRLVD------GKPPPRPKFGPKWRFNQYHN 130

  Fly   110 RGRTGRGTPNIASLGGSTAGGATASTTKYGKGR---NTRNTQNMGRRFGRNAPTRIRESSVMVQS 171
            |.:..:.......     |....|...:..:.|   |.||..:..||     .....:|||.:|.
plant   131 RNQLPQRRDEEVE-----AKKREAEKDRARRDRLYNNNRNNIHQQRR-----EAAAFKSSVDIQP 185

  Fly   172 DWVSIEEIDFPRLLKLALPNIKDGKDIATCGWLEFYDKLYDRVNLRNEKPLQKMDRVVHTVTTTD 236
            :|..:|:|.|....||:. .:.:.:|:..||.||.||:.:||:..:.::.|::.......|||:|
plant   186 EWNMLEQIPFSTFSKLSF-TVSEPEDLLLCGGLESYDRSFDRITPKADRRLERFKNRSFKVTTSD 249

  Fly   237 DPVIRRLSR-TMGNVFATDEILSTIMCCTRSNYSWDVVVEKLGTKVFLDKRYNDQFDLLTVNETS 300
            |.|||||:: ....|||||.||:.:||..||.||||:|::::|.|:|.|||.....|||:|:|||
plant   250 DLVIRRLAKEDKATVFATDAILAALMCAPRSVYSWDLVIQRVGNKLFFDKRDGSPLDLLSVHETS 314

  Fly   301 VEPPMDEEGSINSAHSLAMEATLINHNFSQQVL-RIGDQEPRFMFEEPNPFEEPGVDLASIGYRY 364
            .||..:.:..|||||||.:||..||.||:|||| :.|.:|   .|:||.|....|.:.|||.|||
plant   315 QEPLPEGKDDINSAHSLGLEAAYINQNFAQQVLVKNGKRE---TFDEPIPNVNEGEENASIAYRY 376

  Fly   365 RQWDLGNDVVLIARCKHNGVIQGPNGDVQFLSIKALNEWDSKVTNSVEWRQKLDTQRGAVLASEL 429
            |:|.|.:.:.|:|||:....:. .|....||::.||||:|.|. :.|:|||||:||||||||:||
plant   377 RRWKLDDSMYLVARCELQSTVD-LNNQRSFLTLNALNEFDPKY-SGVDWRQKLETQRGAVLANEL 439

  Fly   430 RNNACKLARWTVEAVLAGSDQLKLGYVSRMNPRDHLRHVILGTQQFKPQEFATQINLNMDNAWGV 494
            :||..|||:||.:|:||.:|.:|:|:|||::||||..||||....:||::||.|||||.:|.||:
plant   440 KNNGNKLAKWTAQALLANADMMKIGFVSRVHPRDHFNHVILSVLGYKPKDFAGQINLNTNNMWGI 504

  Fly   495 LRCLIDLVMRQPDGKYLIMKDPNKPMIRLYDVPENAFDSDGDEE-----------EESSDPLSNS 548
            ::.::||.|:..:|||:::|||:||.:|:|:||.:|||:|..||           ||::|..:.:
plant   505 VKSIVDLCMKLSEGKYVLVKDPSKPQVRIYEVPADAFDNDYVEEPLPEDEQVQPPEENTDAGAET 569

  Fly   549 N 549
            |
plant   570 N 570

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3d2	NP_731675.1	eIF-3_zeta	7..525	CDD:282888	212/549 (39%)
AT5G44320	NP_199245.1	eIF-3_zeta	6..535	CDD:398661	212/549 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	397	1.000	Domainoid score	I139
eggNOG	1	0.900	-	-		E1_KOG2479
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	412	1.000	Inparanoid score	I450
OMA	1	1.010	-	-		QHG53861
OrthoDB	1	1.010	-	-		D1030308at2759
OrthoFinder	1	1.000	-	-		FOG0004086
OrthoInspector	1	1.000	-	-		mtm989
orthoMCL	1	0.900	-	-		OOG6_102252
Panther	1	1.100	-	-	O	PTHR12399
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2834
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840