Protein Alignment eIF3d2 and Eif3d

DIOPT Version :10

• Sequence 1: NP_731675.1
• Gene: eIF3d2 / 41475
• FlyBaseID: FBgn0037994
• Length: 551
• Species: Drosophila melanogaster
• Sequence 2: NP_061219.2
• Gene: Eif3d / 55944
• MGIID: 1933181
• Length: 548
• Species: Mus musculus
• Alignment Length: 550
• Identity: 295/550 - (53%)
• Similarity: 394/550 - (71%)
• Gaps: 23/550 - (4%)

  Fly     5 APFIKPYVEYNEHGWGPCEVPE--LDVPYQPFCKSDRLGKICDWT-AMVPEKKFPSKYASTFGNN 66
            |.|:.|.::.|..|||||.|||  .|:|||||.|.|||||:.||| |...:|::.:||:|.||..
Mouse     2 AKFMTPVIQDNPSGWGPCAVPEQFRDMPYQPFSKGDRLGKVADWTGATYQDKRYTNKYSSQFGGG 66

  Fly    67 SQYAYFYEDDDSTFHLVDTTGSKATKPYQRGRYRPNMRNNVRSRGRTGRGTPNIASLGGSTAGGA 131
            ||||||:|:|:::|.||||..::.| .|||.|.|...||..|.:.|......|:.:|
Mouse    67 SQYAYFHEEDETSFQLVDTARTQKT-AYQRNRMRFAQRNLRRDKDRRNMVQFNLQTL-------- 122

  Fly   132 TASTTKYGKGRNTRNTQNMGRRFG-----RNAPTRIRESSVMVQSDWVSIEEIDFPRLLKLALPN 191
             ..:.|..:....|..:...::||     .....:.|:|||.|:|||...||:|||:|:|:....
Mouse   123 -PKSAKQKERERIRLQKKFQKQFGVRQKWDQKSQKPRDSSVEVRSDWEVKEEMDFPQLMKMRYLE 186

  Fly   192 IKDGKDIATCGWLEFYDKLYDRVNLRNEKPLQKMDRVVHTVTTTDDPVIRRLSRTMGNVFATDEI 256
            :.:.:||..||.||:|||.:||:..|:||||:.:.|:.||||||||||||:|::|.|||||||.|
Mouse   187 VSEPQDIECCGALEYYDKAFDRITTRSEKPLRSIKRIFHTVTTTDDPVIRKLAKTQGNVFATDAI 251

  Fly   257 LSTIMCCTRSNYSWDVVVEKLGTKVFLDKRYNDQFDLLTVNETSVEPPMDEEGSINSAHSLAMEA 321
            |:|:|.||||.||||:||:::|:|:|.|||.|..||||||:||:.|||.||..|.||..:|||||
Mouse   252 LATLMSCTRSVYSWDIVVQRVGSKLFFDKRDNSDFDLLTVSETANEPPQDEGNSFNSPRNLAMEA 316

  Fly   322 TLINHNFSQQVLRIGDQEPRFMFEEPNPFEEPGVD---LASIGYRYRQWDLGNDVVLIARCKHNG 383
            |.||||||||.||:|.:  |:.|..||||.|..:|   :||:.||||:|.||:|:.||.||:|:|
Mouse   317 TYINHNFSQQCLRMGRE--RYNFPNPNPFVEDDMDKNEIASVAYRYRRWKLGDDIDLIVRCEHDG 379

  Fly   384 VIQGPNGDVQFLSIKALNEWDSKVTNSVEWRQKLDTQRGAVLASELRNNACKLARWTVEAVLAGS 448
            |:.|.||:|.|::||.||||||:..|.|:||||||:|||||:|:||:||:.||||||..|:||||
Mouse   380 VMTGANGEVSFINIKTLNEWDSRHCNGVDWRQKLDSQRGAVIATELKNNSYKLARWTCCALLAGS 444

  Fly   449 DQLKLGYVSRMNPRDHLRHVILGTQQFKPQEFATQINLNMDNAWGVLRCLIDLVMRQPDGKYLIM 513
            :.||||||||.:.:|..||||||||||||.|||:||||:::||||:|||:||:.|:..:|||||:
Mouse   445 EYLKLGYVSRYHVKDSSRHVILGTQQFKPNEFASQINLSVENAWGILRCVIDICMKLEEGKYLIL 509

  Fly   514 KDPNKPMIRLYDVPENAFDSDGDEEEESSD 543
            |||||.:||:|.:|:..|.|:.|||:|..:
Mouse   510 KDPNKQVIRVYSLPDGTFSSEEDEEDEEEE 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF3d2	NP_731675.1	eIF-3_zeta	7..525	CDD:461547	286/528 (54%)
Eif3d	NP_061219.2	eIF-3_zeta	4..521	CDD:461547	286/528 (54%)
		RNA gate. /evidence=ECO:0000250|UniProtKB:K7IM66	285..299		9/13 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	523..548		7/16 (44%)